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University of Groningen Learning from reward and prediction Geugies, Hanneke

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University of Groningen

Learning from reward and prediction

Geugies, Hanneke

DOI:

10.33612/diss.117800987

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Geugies, H. (2020). Learning from reward and prediction: insights in mechanisms related to recurrence vulnerability and non-response in depression. Rijksuniversiteit Groningen.

https://doi.org/10.33612/diss.117800987

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Insights in mechanisms related to recurrence

vulnerability and non-response in depression

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ISBN printed version 978-94-034-2423-1 ISBN digital version 978-94-034-2422-4

© A. J. Geugies, Groningen 2020

Cover design Concept: We Are Pi, Photography: Bill Tanaka

Lay-out Ellen Beck, www.ellenbeck.nl

Printed by Netzodruk, www.netzodruk.nl

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Table of Content

Part I

Pathophysiological mechanism behind reward processing and reward-related learning

Part II

Prediction of response to treatment in mdd Chapter 01 7

General Introduction

Chapter 02 21 Decreased reward circuit

connectivity during reward anticipation in major depression Manuscript submitted for publication

Chapter 05 83 Validity of the Maudsley Staging

Method in predicting treatment resistant depression outcome using the Netherlands Study of Depression and Anxiety

J Clin Psychiatry 2018; 79(1): 17m11475 Chapter 03 39

Impaired reward-related learning signals in remitted unmedicated patients with recurrent depression

Brain 2019; 142(8): 2510-2522

Chapter 06 101 Decreased functional connectivity of the insula within the salience network as an indicator for prospective insufficient response to antidepressants

NeuroImage Clinical 2019; 24:102064. Chapter 04 63

Aberrant aversive learning signals in the habenula in remitted unmedicated patients with recurrent depression Manuscript submitted for publication

Chapter 07 123 General discussion

Referenties 136, Nederlandse samenvatting 150, Dankwoord 160, Curriculem vitae 164, List of publications 166

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