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Cover Page

The handle http://hdl.handle.net/1887/37040 holds various files of this Leiden University dissertation

Author: Ercan, Ayşe Ece

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List of publications

[1] E.B. Aksel, A.N. Turkoglu,A.E. Ercan, A. Akin, "Localization of an absorber in a turbid semi- infinite medium by spatially resolved continuous-wave diffuse reflectance measurements", J.

Biomed. Opt. 2011 Aug; 16(8):086010.

[2] I. Ronen, E. Ercan, A. Webb, "Axonal and glial microstructural information obtained with diffusion-weighted magnetic resonance spectroscopy at 7T", Frontiers in Integrative Neuroscience 2013 Mar 13; 7(13).

[3] I. Ronen, E. Ercan, A. Webb, "Rapid multi-echo measurement of brain metabolite T2 values at 7T using a single-shot spectroscopic Carr-Purcell-Meiboom-Gill sequence and prior information", NMR in Biomedicine 2013 Oct; 26(10):1291-8.

[4] F. Branzoli, E. Ercan, A. Webb, I. Ronen, "The interaction between apparent diffusion coefficients and transverse relaxation rates of human brain metabolites and water studied by diffusion-weighted spectroscopy at 7T", NMR in Biomedicine 2014 May; 27(5):495-506.

[5] A.E. Ercan, A. Techawiboonwong, M.J. Versluis, A.G. Webb, I. Ronen, "Diffusion-weighted chemical shift imaging of human brain metabolites at 7T", Magnetic Resonance in Medicine 2015 Jun; 73(6):2053-61.

[6] I. Ronen, M. Budde,E. Ercan, J. Annese, A. Techawiboonwong, A. Webb, "Microstructural organization of axons in the human corpus callosum quantified by diffusion-weighted magnetic resonance spectroscopy of N-acetylaspartate and post-mortem histology", Brain Structure and Function 2014 Sep; 219(5):1773-85.

[7] E. Ercan, I. Carson, O. Tritanon, C. Magro-Checa, A. Smith, S. Smith, T. Huizinga, M.A. van Buchem, I. Ronen, "A multimodal approach to identify and characterize microstructural brain changes in Neuropsychiatric Systemic Lupus Erythematosus", Neuroimage: Clinical, 2015;

8:337-344.

[8] E.T. Wood,A.E. Ercan, F. Branzoli, A. Webb, P. Sati, D.S. Reich, I. Ronen, "Reproducibility and Optimization of In Vivo Human Diffusion-Weighted Magnetic Resonance Spectroscopy of the Corpus Callosum at 3T and 7T", NMR in Biomedicine, 2015 Aug; 28(8):976-87.

[9] A.E. Ercan, C. Magro-Checa, R. Valabregue, F. Branzoli, E.T. Wood, G.M. Steup-Beekman, A.

Webb, T. Huizinga, M.A. van Buchem, I. Ronen, "Glial and Axonal Changes in Systemic Lupus Erythematosus Measured With Diffusion of Intracellular Metabolites", Brain, under review.

[10] E.T Wood,A.E. Ercan, P. Sati, I.C.M. Cortese, I. Ronen, D.S. Reich, "Longitudinal imaging of neurodegeneration in multiple sclerosis with diffusion of intra-axonal constituents", Brain, under review.

[11] C. Magro-Checa,E. Ercan, R. Wolterbeek, B. Emmer; N.J. van der Wee, H.A. Middelkoop, N.D. Kruyt, I. Ronen, M.A. van Buchem, T.W.J. Huizinga, G.M. Steup-Beekman, "Changes in white matter microstructure suggest inflammatory origin of neuropsychiatric systemic lupus erythematosus" Arthritis & Rheumatology, under review.

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Curriculum Vitae

Ay¸se Ece Ercan was born on 31stof July 1983 in Istanbul, Turkey. In 2004, she graduated from Robert College of Istanbul. In 2008, she completed her BSc. degree in Physics at Bo˘gaziçi University with honors and started the Biomedical Engineering Master Program at Delft University of Technology. She conducted her master thesis research at the division of image processing (LKEB), Department of Radiology, Leiden University Medical Center.

In 2010, she received her MSc. degree in Biomedical Engineering from Delft University of Technology. In 2011, she started her PhD at C.J. Gorter Center for high field MRI, Department of Radiology, Leiden University Medical Center. Upon the completion of her PhD, she will start conducting post-doctoral research at the Radiology Department of University of Texas Southwestern Medical Center.

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Acknowledgements

I would like to take the opportunity to thank everyone who was involved in the realization of this thesis: Itamar Ronen, Andrew Webb, Mark van Buchem, Tom Huizinga, César Magro-Checa, Bart Emmer, Jasper Luyendijk, Margreet Steup-Beekman, Liesbeth Beaart- van de Voorde, Emily Wood, Francesca Branzoli, Sophie Schmid, Thijs van Osch, Oranan Tritanon, Carson Ingo, Maarten Versluis, Aranee Techawiboonwong, Wouter Teeuwisse, Iris Asllani, Mathijs Buijs, Nathalie Doorenweerd, Hermien Kan, Gerda Labadie, Michèle Huijberts, Led Zeppelin and Franz Ferdinand. Dear Itamar and Andrew, I feel very lucky to have had the chance to work with you. I learned a great deal about life and science from both of you. Everybody in Gorter Center and LKEB, I am really thankful to you for making the last 5 years really enjoyable, ‘gezellig’ and a lot of fun. I would like to thank Thijs van Osch and Sophie Schmid also for the dutch summary, Vikas Gupta and René Hiemstra for helping with the layout and Sezin Belda˘g for all the time and effort that she put in preparing the cover of this thesis. Çocuklar, Müge and Hilal, thank you for all your endless support and making me feel at home in Leiden. Asena, Ahu, Esra, Belgin, Barı¸s, Tanju, Berrin, Damla, Jale and Meriç, I always felt your presence no matter how far I went so far. Ans, Rinke, Miriam, Erwin, Hendrik and Jeltsje, thank you for being my family here. Dear René, thanks a lot for always being there and taking care of me. Lastly, without the ‘tea sessions’, this thesis would have never existed, I am really grateful for them.

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