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University of Groningen Pulmonary Nodules: 2D versus 3D evaluation in lung cancer screening Han, Daiwei

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University of Groningen

Pulmonary Nodules: 2D versus 3D evaluation in lung cancer screening

Han, Daiwei

DOI:

10.33612/diss.172563513

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

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Publication date:

2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Han, D. (2021). Pulmonary Nodules: 2D versus 3D evaluation in lung cancer screening. University of

Groningen. https://doi.org/10.33612/diss.172563513

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559233-L-st-Han 559233-L-st-Han 559233-L-st-Han 559233-L-st-Han Processed on: 31-5-2021 Processed on: 31-5-2021 Processed on: 31-5-2021

Processed on: 31-5-2021 PDF page: 1PDF page: 1PDF page: 1PDF page: 1

PULMONARY NODULES

2D versus 3D evaluation in lung cancer screening

STATEMENTS

1. LDCT screening is the best option at reducing lung cancer related mortality.

2. All medical societies should recommend volumetric assessment over diameter measurements in lung cancer screening and for early detection. (This thesis)

3. Reliable measurement of lung nodule size is essential for the lung cancer probability assessment and nodule management. (This thesis)

4. It is almost impossible to evaluate nodule growth rate using diameter assessment method at the relevant threshold sizes of the nodule. (This thesis)

5. Ultralow-dose CT with Advanced Modeled Iterative Reconstruction can be utilized for lung cancer screening as nodule detectability and nodule volumetry are not compromised. (This thesis) 6. Lung cancer probability of perifissual nodules is comparable to lung cancer probability of screening

participants with no nodules in a lung cancer screening program. (This thesis)

7. A distinction should be made between typical and atypical PFNs because atypical PFNs have higher malignancy rate. Therefore, misclassification leads to a higher false negative rate of lung cancer.

(This thesis)

8. There is a potential utility of PFN-CNN in lung cancer screening for ruling out benign pulmonary nodules and reduce workload of radiologists. (This thesis)

9. An ounce of prevention is worth a pound of cure. - Benjanmin Franklin

10. If you are not prepared to be wrong, you will never come up with anything original. – Ken Robinson

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