University of Groningen
Development and applications of novel strategies for the enhanced mass spectrometric
quantification of biogenic amines
van Faassen, Martijn
DOI:
10.33612/diss.134196271
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Publication date:
2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
van Faassen, M. (2020). Development and applications of novel strategies for the enhanced mass
spectrometric quantification of biogenic amines. University of Groningen.
https://doi.org/10.33612/diss.134196271
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Development and applications of novel strategies
for the enhanced mass spectrometric quantification of biogenic amines
COLOFON
Development and applications of novel strategies
for the enhanced mass spectrometric quantification of biogenic amines
Martijn van Faassen
Copyright © 2020 Martijn van Faassen
All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any way or by any means without the prior permission of the author, or when applicable, of the publishers of the scientific papers. The author gratefully acknowledges the financial support for printing this thesis by:
Spark Holland B.V. Waters Corporation
Cover design by Harma Makken
Layout and design by Harma Makken, persoonlijkproefschrift.nl Printing: Ridderprint | www.ridderprint.nl
Development and applications of
novel strategies for the enhanced
mass spectrometric quantification
of biogenic amines
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op woensdag 14 oktober 2020 om 16.15 uur
door
Hermannus Johannes Roelof van Faassen
geboren op 11 april 1980TABLE OF CONTENTS
Chapter 1 General introduction and outline of the thesis 6 Chapter 2 Quantitative profiling of platelet-rich plasma indole markers in patients with
neuroendocrine tumors by direct-matrix derivatization combined with LC-MS/MS Clin. Chem. 2019; 65(11): 1388-1396
16
Chapter 3 In matrix derivatization combined with LC-MS/MS results in ultrasensitive quantification of plasma catecholamines and metanephrines
Anal. Chem. 2020; 92(13): 9072-9078
42
Chapter 4A Relationship between plasma and salivary melatonin and cortisol investigated by LC-MS/MS
Clin Chem Lab Med. 2017; 55(9): 1340-1348
74
Chapter 4B Melatonin is not stored in platelets Clin Chim Acta. 2019; 498: 17-20
94
Chapter 5 Mass spectrometric quantification of urinary 6-sulfatoxymelatonin: Age-dependent excretion and biological variation
Clin Chem Lab Med. 2020 Jul 16. doi: 10.1515/cclm-2020-0455
104
Chapter 6 Use of selective serotonin reuptake inhibitors is associated with very low plasma free serotonin concentrations in humans
Ann Clin Biochem. 2020; 57(1): 59-63
124
Chapter 7 Platelet serotonin concentrations are lower in renal cell carcinoma and pancreatic neuroendocrine tumor patients compared to healthy individuals: a role for indoleamine 2,3-dioxygenase
134
Chapter 8 Effective niacin (vitamin B3) suppletion in patients with serotonin producing neuroendocrine tumors
Neuroendocrinology. 2016; 103(5): 489-494
154
Chapter 9 Summary and future perspectives 168
Chapter 10 Nederlandse samenvatting (Dutch summary) 182
Dankwoord (Acknowledgments) 192
List of publications 200
