DNA mismatch repair and the cellular response to UVC radiation Borgdorff, Viola

If  the  MMR  proteins  are  rather  involved  in  the  removal  of  mismatches  opposite  UVC‐induced  photolesions  than  involved  in  signalling  to 

Our patient’s tumors showed in two tumors CTNNB1 as well as MLH1 pathogenic variants, but only in the colon tumor a TP53 pathogenic variant was identified. The presence of

The results of the study are: (1) a university art center can become a center of art resources in the community, thanks to its attributes and develop partnerships with

Potential students and their parents can receive information about the content of the different study programmes and requirements of access to this institution via

b Department of Toxicogenetics, Leiden University Medical Center, LUMC Building 2, P.O. However, the factors that determine and execute JNK- and ERK-controlled stress responses are

The work presented in this thesis has focused on the role of Mitogen Activated Protein Kinases (MAPKs) and their major downstream targets, the AP-1 transcription factors,

Thus, absence of ATM and Nibrin1 in human diploid fibroblasts does not cause a general defect in IR-induced gene expression, but rather specifically blocks IR-induced activation of

b Department of Toxicogenetics, Leiden University Medical Center, LUMC Building 2, P.O. However, the factors that determine and execute JNK- and ERK-controlled stress responses are