Clinical, pathological and molecular prognostic factors in colorectal cancer

Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels have

In this study, we have compared visual examination of CK-immunostained serial sections (as gold standard) with au- tomated analysis and with the RT-PCR data from the referred

Using these three aberrations 10 out of 17 (59%) BM-positive patients could be identified as high-risk for the presence of disseminated tumor cells in the BM compared to 2 out of

Methods: In a retrospective study of 63 patients with colon cancer (stage I–III, 1990–2001) the carcinoma-percentage of the primary tumor was estimated on routine H&E

We have analyzed 135 stage I-II colon cancer patients with at least 11 years of follow-up for the proportion of tumor related stroma and for TGF-B-R2, SMAD4 and B-catenin.. It

Biological parameters such as the presence of micrometastases in lymph nodes, dissem- inated cells in bone marrow and circulating tumor cells in peripheral blood have shown to be

In hoofdstuk 3 wordt automatische microscopie toegepast voor het vinden van micrometastasen in de lymfeklieren van stadium II patiënten om patiënten te identificeren met een

Oosterwijk JC, Mesker WE, Ouwerkerk-van Velzen MC, Knepfle CF, Wiesmeijer KC, van den Burg MJ, Beverstock GC, Bernini LF, Van Ommen GJ, Kanhai HH, Tanke HJ: Development of