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VU Research Portal

Diffusion-weighted MRI and 18F-FDG-PET-CT in head and neck cancer

Schouten, C.S.

2017

document version

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Link to publication in VU Research Portal

citation for published version (APA)

Schouten, C. S. (2017). Diffusion-weighted MRI and 18F-FDG-PET-CT in head and neck cancer: Prediction and response evaluation.

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T

ABLE OF CONTENTS

CHAPTER 1 General introduction and outline of thesis 9

P

ART

1

P

REDICTION PRIOR TO TREATMENT 37

CHAPTER 2 Interaction of quantitative 18F-FDG-PET-CT imaging parameters and human papillomavirus status in oropharyngeal squamous cell carcinoma

39

CHAPTER 3 Quantitative diffusion-weighted MRI parameters and human papillomavirus status in oropharyngeal squamous cell carcinoma

57

P

ART

2

P

REDICTION DURING TREATMENT 71

CHAPTER 4 Diffusion-weighted EPI- and HASTE-MRI and

18

F-FDG-PET-CT early during chemoradiotherapy in advanced head and neck cancer

73

P

ART

3

R

ESPONSE EVALUATION 99

CHAPTER 5 Response evaluation after chemoradiotherapy for advanced staged oropharyngeal squamous cell carcinoma: a nationwide survey in the Netherlands

101

CHAPTER 6 Response evaluation after chemoradiotherapy for advanced stage oropharyngeal squamous cell carcinoma using 18F-FDG-PET-CT and diffusion-weighted MRI: the REACTION-study

117

CHAPTER 7 Response evaluation after chemoradiotherapy for advanced nodal disease from head and neck squamous cell carcinoma using diffusion-weighted MRI and 18F-FDG-PET-CT

139

CHAPTER 8 Cost-effectiveness of response evaluation after chemoradiation in patients with advanced oropharyngeal cancer using 18F-FDG-PET-CT and diffusion-weighted MRI

161

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CHAPTER 9 Summary and future perspectives

Nederlandse samenvatting en toekomstperspectief

183 193

APPENDIX Acknowledgments │ Dankwoord 205

Curriculum Vitae 213

List of publications 215

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