Cover Page
The following handle holds various files of this Leiden University dissertation:
http://hdl.handle.net/1887/79946
Author: Skvortsova, A.
Author: Aleksandrina Skvortsova
Cover design: Aleksandrina Skvortsova, Lolita Dezegher Printing: GVO Drukkers & Vormgevers BV © Copyright Aleksandrina Skvortsova, 2019
All rights reserved. No part of this thesis may be reproduced or transmitted in any form or by any means without written permission from the author.
The research presented in this thesis was carried out at the Health, Medical and
Placebo Effects and the Endocrine System:
the Role of Oxytocin
Proefschrift
Ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op dinsdag 29 oktober 2019
klokke 15:00 uur
door
Aleksandrina Skvortsova
Promotor
Prof. Dr. A.W.M. Evers
Table of Contents:
Chapter 1 Introduction 7
Part I Conditioning of oxytocin and other endocrine responses 25 Chapter 2 Conditioned hormonal responses: a systematic review in animals
and humans 27
Chapter 3 Placebo effects in the neuroendocrine system: conditioning of the
oxytocin responses 63
Chapter 4 Effects of oxytocin administration and conditioned oxytocin on
brain activity: an fMRI study 87
Part II Influencing placebo effects with oxytocin 121 Chapter 5 Enhancing placebo effects in somatic symptoms through
oxytocin 123
Chapter 6 Effects of oxytocin on placebo and nocebo effects in a pain
conditioning paradigm 145
Chapter 7 Summary and General discussion 163
Nederlandse Samenvatting 185
Curriculum Vitae 191