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EEG during memory activation: a study of early functional brain changes in Alzheimer's disease and Huntington's disease

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EEG during memory activation: a study of early functional

brain changes in Alzheimer's disease and Huntington's

disease

Hiele, K. van der

Citation

Hiele, K. van der. (2007, November 29). EEG during memory activation: a study of early functional brain changes in Alzheimer's disease and

Huntington's disease. Retrieved from https://hdl.handle.net/1887/12468

Version: Not Applicable (or Unknown)

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/12468

Note: To cite this publication please use the final published version (if applicable).

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Acknowledgements

List of publications

Curriculum Vitae

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Acknowledgements

First of all, I would like to thank all participants in the EEG study.

Without their cooperation this research project would not have been possible.

I greatly appreciate the help of several colleagues. In particular, I thank P.J. van Someren, J.G. van Vliet-de Regt, M.J. Stijl-Pek, F.I. Kerkhof, and G.H. van Beukering-Louwes for their help with EEG registration.

Furthermore, I am grateful to Cor Kramer for his technical assistance and modeling work. I am particularly grateful to Emma Tiesma and Annemiek van der Welle, two students who based their master’s thesis on the current study. We were able to include several patients of the Diaconessenhuis and Leyenburg hospital. This would not have been possible without the help of Bas de Bruijn, Marijke Pleket, Annelies Weverling-Rijnsburger en Jacqueline Mulder.

Finally, I would like to thank all my colleagues at the Neuropsychology sections of Leiden University and the Leiden University Medical Center for their daily support.

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List of publications

1. van der Hiele K, Vein AA, van Dijk JG, Middelkoop HAM.

Kwantitatieve elektroencefalografie als hulpmiddel bij de vroege diagnostiek van Alzheimer-type dementie. Neuropraxis 2004;8(2):41-7.

2. van der Hiele K, Vein AA, Kramer CGS, Reijntjes RHAM, van Buchem MA, Westendorp RGJ, Bollen ELEM, van Dijk JG, Middelkoop HAM.

Memory activation enhances EEG abnormality in mild cognitive impairment. Neurobiol Aging 2007;28(1):85-90.

3. van der Hiele K, Vein AA, van der Welle A, van der Grond J, Westendorp RGJ, Bollen ELEM, van Buchem MA, van Dijk JG, Middelkoop HAM. EEG and MRI correlates of mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 2006;28(9):1322-9.

4. van der Hiele K, Jurgens CK, Vein AA, Reijntjes RHAM, Witjes-Ané MNW, Roos RAC, Van Dijk JG, Middelkoop HAM. Memory activation reveals abnormal EEG in preclinical Huntington’s disease. Mov Disorders 2007;22(5):690-5.

5. van der Hiele K, Vein AA, Reijntjes RHAM, Westendorp RGJ, Bollen ELEM, van Buchem MA, van Dijk JG, Middelkoop HAM. EEG correlates in the spectrum of cognitive decline. Clin Neurophysiol 2007;118(9):1931-9.

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Curriculum Vitae

Karin van der Hiele was born on the 27th of July 1976 in Rotterdam. In 1994 she received her Gymnasium diploma at the secondary school

‘Hugo de Groot’ in Rotterdam. A year later she started her degree in Psychology at Leiden University and eventually specialized in Cognitive Psychology. In her final year she was given the opportunity to do a research project and clinical internship at the department of Neurology, Neuropsychology at the Leiden University Medical Center (LUMC). This research project concerned an EEG study on vigilance in patients with narcolepsy. After her cum laude graduation in 1999 she began a postdoctoral degree in ‘User-System Interaction’ at the Technical University of Eindhoven. Her final project concerned the development of a speech-based interface. After her graduation she worked as a usability researcher for ‘Meru Research’ where she was involved in the development of a patent search engine for the European Patent Office.

In 2003 she was given the opportunity to start a PhD project at the department of Clinical, Health and Neuropsychology at Leiden University and the department of Neurology, Neuropsychology at the LUMC. This research was aimed at finding predictors of cognitive decline and Alzheimer’s disease using both functional MRI and quantitative EEG. In 2006 she accepted a part-time teaching position at Leiden University in combination with her PhD position.

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