Innate Immune Memory and Transcriptional Profiling of Microglia
Heng, Yang
DOI:
10.33612/diss.151944032
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Publication date:
2021
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Heng, Y. (2021). Innate Immune Memory and Transcriptional Profiling of Microglia. University of Groningen.
https://doi.org/10.33612/diss.151944032
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Innate Immune Memory and
Transcriptional Profiling of Microglia
The research presented in this thesis was conducted at the Section Molecular Neurobiology, Department Biomedical Sciences of Cells & Systems, University Medical Center Groningen, University of Groningen, The Netherlands.
The research in this thesis was financially supported by the China Scholarship Council and University Medical Center Groningen.
Printing Ridderprint
Cover design Yang Heng
On the Cover On the front cover, the two clouds represent the immune training
response of microglia. After the first challenge, microglia show enhanced response to a sequential challenge. The transition of Yin-Yang represents the phenotypical change of microglia. The six microglia in Yin-Yang represent microglia phenotypic diversity. The transition of cold-warm color in the background is also inspired by Yin-Yang theory.
On the back cover, the two clouds represent the immune tolerance response of microglia. The windmill at the bottom left corner is inspired by the Windmill ‘De Helper’ in Paterswoldsemeer, Groningen. Financial support University of Groningen University Medical Center Groningen Research School of Behavioral and Cognitive Neurosciences Copyright © 2021 by Yang Heng. All rights reserved. No part of this thesis may be reproduced or transmitted in any form or by any means without prior permission of the author and the publishers holding the copyrights of the published articles.
