University of Groningen
Optimizing the treatment strategy of breast cancer
Qiu, Si-Qi
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
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Qiu, S-Q. (2019). Optimizing the treatment strategy of breast cancer. Rijksuniversiteit Groningen.
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PROPOSITIONS
Belonging t0 the PhD thesis
Optimizing the treatment strategy of breast cancer
1. The trend of de-escalation in the surgical treatment of breast cancer is irreversible (this thesis).
2. Further refinement of systemic therapy for breast cancer requires better understanding of characteristics of the tumor and its associated microenvironment (this thesis).
3. A model-based approach can preoperatively predict the risk of axillary lymph node metastasis and serve as a tool to identify a group of low-risk patients who are candidates for the omission of axillary surgery (Chapter 3 and Chapter 4 of this thesis).
4. Near-infrared molecular fluorescence-guided surgery using bevacizumab-800CW can support improved intraoperative surgical margin assessment in breast-conserving surgery (Chapter 6 of this thesis).
5. Based on tumor androgen receptor expression and the composition of infiltrated immune cells, different subsets of HER2 positive breast cancers can be identified (Chapter 8 of this thesis).
6. Surgeons have to be educated to accept more limited surgery for breast cancer (Morrow M et al. JAMA Oncol., 2018).
7. A good sleep can not only keep your mind, but also your blood vessels healthy (Cameron S et al. Nature, 2019).
8. Although discovery of molecular mechanisms of disease is increasingly important for optimal treatment selection for individual patients, the clinicians’ assessment should remain decisive.
9. Artificial intelligence is a sensitive third eye of clinicians to improve detection, characterization and monitoring of tumors; as such it should be incorporated into clinical practice.
10. Everyone should take good control of their cell phone; otherwise it will take control of us.
11. Study without thinking is labor lost. Thinking without study is perilous. - Confucius <Lun Yu>. 学而不思则罔，思而不学则殆。- 孔子，《论语》
Siqi Qiu
