University of Groningen
Optimizing the treatment strategy of breast cancer
Qiu, Si-Qi
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Publication date: 2019
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Qiu, S-Q. (2019). Optimizing the treatment strategy of breast cancer. Rijksuniversiteit Groningen.
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Optimizing the treatment
strategy of breast cancer
Qiu, S
Optimizing the treatment strategy of breast cancer
Thesis, University of Groningen, Groningen, The Netherlands
Printing of this thesis was financially supported by the University of Groninge, the Graduate School of Medical Sciences and the Stichting Werkgroep Interne Oncologie, UMCG.
Cover Siqi Qiu
Layout Siqi Qiu
Printed by Ridderprint
ISBN: 978-94-034-1401-0
ISBN (electronic version): 978-94-034-1400-3 © 2019, S Qiu
All rights reserved. No part of this thesis may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanically, by photocopying, recording, or otherwise, without prior written permission of the author.
Optimizing the treatment strategy
of breast cancer
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the prof. dr. E. Sterken and in accordance with the decision by the College of Deans. This thesis will be defended in public on
Wednesday 1 May 2019 at 14.30 hours
by
Siqi Qiu
born on 9 March 1987 in Guangdong, China
Promotores
Prof. dr. E.G.E. de Vries Prof. dr. G.M. van Dam
Copromotor Dr. C.P. Schröder Assessment Committee Prof. dr. L.P. Stassen Prof. dr. S. de Jong Prof. dr. H. Hollema
Dedicated to My Family
谨以此书献给我亲爱的家人
Paranymphs
Frans Suurs Yuanke Liang
CONTENTS
Chapter 1 General introduction 9
Chapter 2 Evolution in sentinel lymph node biopsy in breast cacer
Crit Rev Oncol Hematol. 2018;123:83-94 17
Chapter 3 A nomogram to predict the probability of axillary lymph node metastasis in early breast cancer patients with positive axillary ultrasound
Sci Rep. 2016;6:21196
49
Chapter 4 Validation and update of a lymph node metastasis prediction model for breast cancer
Eur J Surg Oncol. 2018;44(5):700-707
71
Chapter 5 Micro-computed tomography (micro-CT) for intraoperative surgical margin assessment of breast cancer: a feasibility study in breast conserving surgery
Eur J Surg Oncol. 2018;44(11):1708-1713
89
Chapter 6 Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
Nat Commun. 2018;9(1):3739
105
Chapter 7 Tumor-associated macrophages in breast cancer: Innocent bystander or important player?
Cancer Treat Rev. 2018;70:178-189
131
Chapter 8 Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer
Eur J Cancer. 2018;103:52-60
161
Chapter 9 Summary and future perspectives 177
Chapter 10 中文总结与展望 (Chinese summary) 189
Chapter 11 Nederlandse samenvatting (Dutch summary) 199
Curriculum vitae 208
Publications 209