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Association between muscle thickness, fat-free mass and malnutrition in patients with copd: an exploratory study

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Non-Cognitive Predictors of Student Success:

A Predictive Validity Comparison Between Domestic and International Students

ASSOCIATION BETWEEN MUSCLE THICKNESS, FAT-FREE MASS AND

MALNUTRITION IN PATIENTS WITH COPD: AN EXPLORATORY STUDY

Non-Cognitive Predictors of Student Success:

A Predictive Validity Comparison Between Domestic and International Students

INTRODUCTION

• Malnutrition is common in patients with Chronic Obstructive Pulmonary Disease (COPD).

• Muscle thickness has been suggested as a parameter for malnutrition

• We explored the association between fat free mass index (FFMI), muscle thickness of biceps brachii (BB) and rectus femoris (RF), and malnutrition in advanced COPD patients

METHODS

• Patients were included at the start of a pulmonary rehabilitation program • Malnutrition was defined as PG-SGA

Stage B or C

• FFMI (kg/m2) was estimated with BIA

101®

• Muscle thickness of BB and RF was measured with BodyMetrix® ultrasound device

• Association between FFMI and RF and BB thickness, and malnutrition was analyzed with uni- and multivariate logistic regression.

• Multivariate analysis corrected for sex, age (years) and GOLD-stadia

RESULTS

• 27 COPD patients (age 64±8.1 years; female 60%; GOLD-stage 3; interquartile range=3-4; BMI 27±6.6kg/m2) were

included in analyses

• Multivariate analysis: FFMI and BB thickness were significantly associated with malnutrition

M. Engels 1, L. Zuurman 2, M. J. Sealy*, 3, J. Plas 4, H. Jager-Wittenaar 3,5, H. van der Vaart 4 1Department of Nutrition and Dietetics, School of Health Care Studies, 2Department of Medical Imaging and

Radiation Therapy, School of Health Care Studies, 3Research Group Healthy Ageing, Allied Health Care and

Nursing, Hanze University of Applied Sciences Groningen, 4Department of Pulmonary Diseases and

Tuberculosis, 5Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical

Center Groningen, Groningen, Netherlands

www.hanze.nl/lahc www.faithresearch.nl www.facebook.com/lahc

www.facebook.com/faithresearch.nl

Figure 2: Image of Rectus Femoris with BodyMetrix

Figure 1: Image of Biceps Brachii with BodyMetrix

Table 1: Logistic regression analyses of FFMI, BB and RF thickness, and malnutrition

REFERENCE

Nijholt W, Beek L ter, Hobbelen JSM, van der Vaart H, Wempe JB, van der Schans CP, et al. The added value of ultrasound muscle measurements in patients with COPD: An exploratory study. Clin Nutr ESPEN 2019;30:152–8

P052

CONCLUSION

In patients with advanced COPD, low FFMI and

low BB muscle thickness were robustly associated

with increased odds of being malnourished

p-value OR [95%CI] Univariate analysis FFMI 0.030* 0.70 [0.52-0.97] m BB thickness 0.023* 0.83 [0.70-0.97] m RF thickness 0.040* 0.79 [0.63-0.99] Multivariate analysis FFMI 0.040* 0.59 [0.35-0.98] m BB thickness 0.036* 0.73 [0.55-0.98] m RF thickness 0.090* 0.76 [0.56-1.04]

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