Development of an anitsense-mediated exon skipping therapy for
Duchenne Muscular Dystrophy.
Aartsma-Rus, A.M.
Citation
Aartsma-Rus, A. M. (2005, February 10). Development of an anitsense-mediated exon
skipping therapy for Duchenne Muscular Dystrophy. Retrieved from
https://hdl.handle.net/1887/604
Version:
Corrected Publisher’s Version
License:
Licence agreement concerning inclusion of doctoral thesis in the
Institutional Repository of the University of Leiden
Downloaded from:
https://hdl.handle.net/1887/604
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Pro efsc h rift
ter verkrijging van
de graad Do c to r aan de Universiteit Leiden
o p gez ag van de Rec to r Magnific us Dr. D.D. B reimer
h o o gleraar in de fac ulteit der W iskunde en
Natuurw etensc h ap p en en die der Geneeskunde,
vo lgens h et b esluit van h et Co llege vo o r Pro mo ties
te verdedigen o p do nderdag 1 0 feb ruari 2 0 0 5 te klo kke 1 6 .1 5 uur
do o r
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Promotiecommissie
Promotor: Prof. Dr. G-J.B. van Ommen Co-promotoren: Dr. J.C.T. van Deutekom
Dr. J.T. den Dunnen
Referent: Prof. Dr. F . Baas (Universiteit van Amsterdam) Overige leden: Prof. Dr. M.H. Breuning
Prof. Dr. K. Bushby (University of N ewcastle Upon Tyne, Engeland)
ISBN 9 0 -8 5 5 9 -0 2 9 -9
Coverart
F ront: AON -treated dystrophin positive myotubes; back: myotube treated with fluorescently labeled AON s (picture taken with help of Gert de V oer)
The studies described in this thesis have been performed at the Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden. The work was financially supported by grants from the Duchenne Parent Project (the N etherlands), the Princess Beatrix F und (the N etherlands), the Muscular Dystrophy Campaign (UK), the Muscular Dystrophy Association (USA) and the European Union (grant no Q LG2 -CT-1 9 9 9 -0 0 9 2 0 )
Prosensa B.V . is gratefully acknowledged for covering part of the printing costs of this thesis
