Neonatal transfusion practices
Lindern, J.S. von
Citation
Lindern, J. S. von. (2011, October 27). Neonatal transfusion practices.
Retrieved from https://hdl.handle.net/1887/17989
Version: Corrected Publisher’s Version License:
Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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Neonatal transfusion practices
ISBN: 978-94-6169-118-7
Layout: Jim Navarro & Optima Grafische Communicatie, Rotterdam, The Netherlands Printing: Optima Grafische Communicatie, Rotterdam, The Netherlands
The publication of this thesis was financially supported by Willem-Alexander Kinderzie- kenhuis Leiden, Nutricia Nederland BV, Abbott BV, Sanquin Bloedvoorziening
©2011 J.S. von Lindern, Leiden, the Netherlands
Jeannette Bw 5.indd 2 26-08-11 16:50
Neonatal transfusion practices
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op donderdag 27 oktober 2011
klokke 13.45 uur
door
Jeannette Susanne von Lindern
geboren te ‘s-Gravenhagein 1967
Promotie commissie
Promotor: Prof. Dr. F.J. Walther Prof. Dr. A. Brand Copromotor: Dr. E. Lopriore
Overige leden: Prof. dr. A.F. Bos, Universitair Medisch Centrum Groningen Dr. H.A.A. Brouwers, Universitair Medisch Centrum Utrecht Dr. J.J. Zwaginga
Prof. Dr. R.R.P. de Vries
Prof. Dr. H.A. Delemarre-van de Waal Dr. D. Oepkes
Jeannette Bw 5.indd 4 26-08-11 16:50
Contents
Chapter 1 General introduction and outline of the thesis 6 Chapter 2 The use of blood products in perinatal medicine 14
Part I Umbilical cord blood
Chapter 3 Potential use of autologous umbilical cord blood red blood cells for early transfusion needs of premature infants
38
Chapter 4 A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity
54
Part II Red blood cells
Chapter 5 A comparative cohort study on transfusion practice and outcome in two Dutch tertiary neonatal centres
76
Chapter 6 Long term outcome in relationship to neonatal transfusion volume in extremely premature infants: a comparative cohort study
90
Chapter 7 Erytrocyten transfusie bij neonaten: huidige praktijk en gereviseerde landelijk richtlijn
102
Part III Platelets
Chapter 8 Thrombocytopenia in neonates and the risk of intraventricular hemorrhage
122
Chapter 9 Intraventricular hemorrhage and thrombocytopenia in very premature infants: a tale of two cities
136
Chapter 10 Trombocyten transfusie bij neonaten: huidige praktijk en gereviseerde landelijk richtlijn
148
Chapter 11 General discussion and future perspectives 164
Chapter 12 Summary 180
Chapter 13 Samenvatting 188
Dankwoord 197