University of Groningen
Ready to administer parenteral medication produced by the hospital pharmacy
Larmené-Beld, Karin
DOI:
10.33612/diss.144367021
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Larmené-Beld, K. (2020). Ready to administer parenteral medication produced by the hospital pharmacy: cost, labeling and quality. University of Groningen. https://doi.org/10.33612/diss.144367021
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
READY TO ADMINISTER
PARENTERAL MEDICATION
PRODUCED BY
THE HOSPITAL PHARMACY:
COST, LABELING AND QUALITY
Ready to administer parenteral medication produced by the hospital pharmacy: cost, labeling and quality
Karin H. M. Larmené- Beld
Thesis, University of Groningen, Groningen, the Netherlands
The work described in this thesis was performed at the department of Clinical pharmacy of Isala hospital Zwolle.
Publication of this thesis was financially supported by the Groningen Graduate School of Science and Engineering (GSSE), the University of Groningen and Stichting Koninklijke Nederlandse Maatschappij ter Bevordering der Pharmacie (KNMP) Fondsen, and is gratefully acknowledged.
Cover image: Frans Larmené
Lay- out: Stefan Heinrich, Publiss
Printed by: Ridderprint BV, www.ridderprint.nl © 2020 Karin Larmené-Beld
All rights reserved. No part of this thesis publication may be reproduced or transmitted in any form or by any means, without prior permission from the author or from the publishers holding the copyright of the published articles.
Ready to administer parenteral
medication produced by the
hospital pharmacy:
cost, labeling and quality
Proefschrift
ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
vrijdag 27 november 2020 om 11.00 uur
door
Karin Hendrika Maria Beld
geboren op 29 mei 1985
Promotores Prof. dr. K. Taxis Prof. dr. M.J. Postma Prof. dr. H.W. Frijlink Beoordelingscommissie Prof. dr. D.J. Touw
Prof. dr. P.M.L.A. van den Bemt Prof. dr. H. Vromans
Paranimfen
Daphne den Besten- Bertholee Douwe van der Meer
CONTENTS
Chapter 1 Introduction and scope of the thesis 9 Chapter 2 A systematic review and meta-analysis of microbial
contamination of parenteral medication prepared in a clinical versus pharmacy environment
European Journal of Clinical Pharmacology 2019; 75:609-617
23
Chapter 3 A cost minimization analysis of ready-to-administer prefilled sterilized syringes in a Dutch hospital Clinical Therapeutics 2019; 41:1139-1150
47
Chapter 4a A systematic literature review on strategies to avoid look-alike errors of labels
European Journal of Clinical Pharmacology 2018; 74:985–993
69
Chapter 4b A survey about label enhancement methods for parenteral medication in Europeanhospital pharmacies
European Journal of Clinical Pharmacology, 2020 Epub, ahead of print
95
Chapter 5 A science and risk based strategy to qualify prefillable autoclavable syringes as primary packaging material
European Journal of Hospital Pharmacy, in press 109
Chapter 6 Prefilled cyclic olefin sterilized syringes of norepinephrine solution do not need to be stabilized by antioxidants
AAPS PharmSciTech 2020; 21:247
135
Chapter 7 General discussion and perspectives 151 Chapter 8 Summary & samenvatting 165
Epilogue 177
Dankwoord 178
About the author 183 List of publications 185
