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Chronic myeloid leukemia: Evolving from fatal stem cell disease to cure
Thielen, N.
2015
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Thielen, N. (2015). Chronic myeloid leukemia: Evolving from fatal stem cell disease to cure.
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CONTENTS
Chapter 1 General introduction and outline of the thesis 9
Chapter 2 Chronic myeloid leukemia in the Netherlands: a population-based study on incidence,treatment and survival in 3,585 patients from 1989-2012
25
Chapter 3 The EUTOS population-based registry: incidence and clinical characteristics of 2,904 CML patients in twenty European countries
43
Chapter 4 High-dose imatinib versus high-dose imatinib in combination with intermediate-dose cytarabine in patients with first chronic phase myeloid leukemia: a randomized phase III trial of the Dutch-Belgian HOVON study group
63
Chapter 5 Imatinib discontinuation in chronic phase myeloid leukaemia patients in sustained complete molecular response: a randomised trial of the Dutch-Belgian Cooperative Trial Group for Haemato-Oncology (HOVON)
79
Chapter 6 New insights in the pathogenesis of chronic myeloid leukemia: towards a path to cure
93
Chapter 7 Leukemic stem cell quantification in newly diagnosed chronic phase chronic myeloid leukemia (CML-CP) predicts response to nilotinib: results from the ENEST1st stem cell substudy
119
Chapter 8 Summary and future perspectives 139
Appendices Samenvatting voor medisch niet-ingewijden 145
Curriculum Vitae 157
List of Publications 161
