Changes in total cerebral blood flow and morphology in aging Spilt, A.

The fl ow values are then calculated by the multiplication of the actual velocity values and the area of the automatically segmented region of interest (ROI). The second,

The main fi nding of the study is that acute hypoxia induced an increase in total CBF that could be blunted by the competitive nitric oxide synthase inhibitor L-NMMA, providing

Second, in contrast to young subjects, in old age basal CBF is depending on the intactness of the nitric oxide pathway, suggesting that cerebral auto regulation

The authors used phase-contrast M RI in 40 NO TCH3 mutation carriers (mean age 45 ± 10 years) and 22 nonmutated family members (mean age 39 ± 12 years), to

If WMH were responsible for the age-related volumetric MTR changes that we observed in the brain, differences in MTR values would have been expected between the elderly subjects

For that purpose we compared MTR values in PVWMH and DWMH, compared MTR values between smooth and irregular PVWMH, between frontal and occipital PVWMH, and between PVWMH

The combined observations of more structural brain damage and lower cerebral blood fl ow in demented elderly individuals than in subj ects of the same age with

I n chapter four, the phase contrast M RI technique for assessing total cerebral blood fl ow was compared with cerebral perfusion imaging in terms of their ability to measure