University of Groningen
Target-based drug discovery: from protein structure to small-molecules by MCR chemistry Wang, Yuanze
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Publication date: 2018
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Wang, Y. (2018). Target-based drug discovery: from protein structure to small-molecules by MCR chemistry. University of Groningen.
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Publication
[1] Wang, Y., Patil, P., Kurpiewska, K., Kalinowska-Tluscik, J., & Dömling, A. (2018) Efficient and Diverse Synthesis of Isoquinoline Derivatives by New Ugi/Pomeranz–Fritsch Multicomponent Reaction. (Submitted)
[2] Wang, Y., Shaabani. S, Moghaddam M. A., Gao. Li, Xu, R. X., Kurpiewska. K, Kalinowska. T. K, Olechno. J, Ellson. R, & Dömling, A. (2018) Acoustic Dispensing-Enabled Reaction Scouting. (Submitted)
[3] Wang, Y., Oosterwijk, N., Ali, A. M., Adawy, A., Anindya, A. L., Dömling, A., & Groves, M. R. (2017). A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables. Scientific Reports, 7(1), 9355. [4] Wang, Y., Patil, P., Kurpiewska, K., Kalinowska-Tluscik, J., & Dömling, A. (2017). Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations. ACS Combinatorial
Science, 19(3), 193-198.
[5] Wang, Y., Patil, P., & Dömling, A. (2016). Easy Synthesis of Two Positional Isomeric Tetrazole Libraries. Synthesis, 48(21), 3701-3712.
[6] Wang, Y., & Ma, S. (2014). Small molecules modulating AHL-based quorum sensing to attenuate bacteria virulence and biofilms as promising antimicrobial drugs. Current medicinal
chemistry, 21(3), 296-311.
[7] Madhavachary, R., Naveen, N., Wang, Y., Wang, Q., Konstantinidou, M., & Domling, A. (2018) -Carbolinone Analogues from the Ugi Silver Mine. European Journal of Organic
Chemistry.
[8]A Meissner, K., Lunev, S., Wang, Y., Linzke, M., de Assis Batista, F., Wrenger, C., & R Groves, M. (2017). Drug Target Validation Methods in Malaria-Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation. Current drug targets, 18(9), 1069-1085.