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Studies on the pathophysiological aspects of the metabolic syndrome in transgenic mice

Hu, L.

Citation

Hu, L. (2009, February 25). Studies on the pathophysiological aspects of the metabolic syndrome in transgenic mice. Retrieved from https://hdl.handle.net/1887/13520

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13520

Note: To cite this publication please use the final published version (if applicable).

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Stellingen

behorende bij het proefschrift

‘Studies on the Pathophysiological Aspects of the Metabolic Syndrome in Transgenic Mice’

1. De metabole relatie tussen plasma PAI-1 levels met insuline resistentie moet heroverwogen worden. (dit proefschrift)

2. Ondanks de atheroprotectieve eigenschappen van LRP, neemt stimulatie van deze receptor risico’s met zich mee. (dit proefschrift)

3. Herstel van de beschadigde vaatwand in patiënten met het metabool syndroom is verstoord. (dit proefschrift)

4. Dat LPL naast lipolyse ook een rol speelt bij de opname van TG rijke deeltjes betekent dat LPL ook pro-atherogene eigenschappen heeft. (dit proefschrift)

5. Dysfunctie van de LDL receptor familie kan leiden tot het metabool syndroom met daarbij behorende risico’s van atherotrombotische events.

6. De lever speelt een belangrijke rol bij het proces van atherosclerose.

7. De LDLR familie gedraagt zich als een stofzuiger voor overtollige plasma eiwitten die hun functie voltooid hebben.

8. De betekenis van energiecrisis in de economie is tegenovergesteld van de betekenis van energiecrisis in de gezondheidszorg.

9. Translationeel onderzoek valt of staat met het verschil in inzichten van de betrokken onderzoekers.

10. Fit is niet vet.

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