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University of Groningen Risk variables for the development of obesity and type 2 diabetes van der Meer, Tom

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University of Groningen

Risk variables for the development of obesity and type 2 diabetes

van der Meer, Tom

DOI:

10.33612/diss.170143787

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

van der Meer, T. (2021). Risk variables for the development of obesity and type 2 diabetes. University of Groningen. https://doi.org/10.33612/diss.170143787

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1. Our body is continuously exposed to a wide variety of potentially hazardous chemicals. (this thesis)

2. Endocrine Disrupting Chemicals (EDCs) have the ability to infiltrate and accumulate in the hypothalamus, an important part of our brain regulating appetite and hunger. (this thesis) 3. Exposure to high concentrations of EDCs is associated with adiposity-related traits, but

evidence regarding type 2 diabetes remains ambiguous. (this thesis)

4. Repeated measurements of EDCs are required to monitor exposure and assess associations with disease. (this thesis)

5. Systematic, data-driven approaches are the only way to disentangle complex, multifactorial diseases. (this thesis)

6. Only a handful of robust risk variables are able to accurately predict future type 2 diabetes. (this thesis)

7. The search for novel risk variables should primarily focus on the aetiology of the disease rather than attempting to outperform existing prediction models. (this thesis)

8. Health is a function of your genome and exposome. (Chirag Patel)

9. When you want to impact the consequences of type 2 diabetes in adults, you should prevent it in childhood.

10. The temptation to form premature theories upon insufficient data is the bane of our profession. (Arthur Conan Doyle)

11. Wie in het dal blijft, ziet nooit de andere kant van de berg. (José de Cauwer)

12. The fact that influenza and RS-virus are non-existent in this winter season proves the benefits of hand hygiene and social distancing.

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