Automated image analysis techniques for cardiovascular magnetic resonance imaging
Geest, R.J. van der
Citation
Geest, R. J. van der. (2011, March 22). Automated image analysis techniques for cardiovascular magnetic resonance imaging. Retrieved from
https://hdl.handle.net/1887/16643
Version: Corrected Publisher’s Version License:
Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/16643
Note: To cite this publication please use the final published version (if
applicable).
Automated Image Analysis Techniques for Cardiovascular
Magnetic Resonance Imaging
Robertus Jacobus van der Geest
2011
Printed by: Drukkerij Mostert & van Onderen, Leiden.
ISBN 978-94-90858-04-9
© 2011, R.J. van der Geest, Leiden, the Netherlands. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system, without prior permission in writing from the copyright owner.
Automated Image Analysis Techniques for Cardiovascular
Magnetic Resonance Imaging
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden
volgens besluit van het College van Promoties ter verdediging op dinsdag 22 maart 2011
klokke 16:15 uur
door
Robertus Jacobus van der Geest geboren te Leiderdorp
in 1966
PROMOTIECOMMISIE
Promotor:
Prof. dr. ir. J.H.C. Reiber
Overige leden:
Prof. dr. A. de Roos Prof. dr. E.E. van der Wall
Prof. dr. A.C. van Rossum VU Medisch Centrum, Amsterdam
The research in this thesis was carried out at the Department of Radiology, Division of Image Processing (LKEB) of the Leiden University Medical Center.
Contents
1 General introduction and outline
Background 8 | Scope of this thesis 9 | Thesis outline 9
7
2 Quantification in cardiac MRI
Introduction 12 | Quantification of ventricular dimensions and global function 12 | Myocardial mass 17 Quantification of ventricular volumes and global function 19 | Quantification of regional wall motion and wall thickening using the centerline method from dynamic short-axis images 21 | Regional function analysis using MRI tagging and velocity-encoded MRI 24 | Automated contour detection in short-axis multi- slice cine-MRI | 26 MRI flow quantification 32 | Image processing of perfusion imaging studies 34 | Late
Gadolinium-enhanced MRI 36 | Integrated image analysis 37 Conclusion 37 | References 38
11
3 Comparison between manual and automated analysis of left ventricular volume parameters from short axis MR images
Introduction 48 | Methods 49 | Statistical analysis 55 Results 56 | Discussion 60 | Conclusion 63
Acknowledgment 63 | References 64
45
4 Automated assessment of MR velocity maps of the ascending aorta: Evaluation of inter- and intraobserver variability in the determination of left ventricular stroke volume by automated and manual analysis methods
Introduction 70 | Methods 71 | Results 77 | Discussion 78 Conclusion 80 | References 80
67
5 Assessment of regional left ventricular wall
parameters from short axis MR imaging using a 3D extension to the improved Centerline method Introduction 86 | Materials 89 | Methods 90 | Statistical analysis 93 | Results 93 | Discussion 98 | Conclusion 101 References 101
83
6 Evaluation of a new method for automated detection of left ventricular boundaries in time series of magnetic resonance images using an active appearance motion model
Introduction 106 | Methods 107 | Statistical analysis 111 Results 112 | Discussion 114 | Conclusion 118
References 118
103
7 Time continuous tracking and segmentation of cardiovascular magnetic resonance images using multi-dimensional dynamic programming
Introduction 124 | Materials and methods 125 Results 134 | Discussion 136 | Conclusion 140 References 141
121
8 Automatic method for the optimization of left
ventricular segmentation in cardiovascular magnetic resonance images
Introduction 146 | Materials 147 | Methods 148 Results 154 | Discussion 156 | Conclusion 158 References 159
143
9 Summary and conclusions
General conclusions 166 161
10 Samenvatting en conclusies
Algemene conclusies 175 169
11 Publications
Refereed papers in international journals 177
Papers in conference proceedings 186 | Book chapters and other publications 187
177
Acknowledgments 189
Curriculum vitae 191
