Development of the sinus venosus myocardium from the posterior second heart field : implications for sinoatrial and atrioventricular mode development

Een abnormale aanleg van het posterior heart field kan resulteren in extra atrioventriculaire myocardiale verbindingen, op deze manier zijn deel I en II in dit proefschrift “extra”

Development of the sinus venosus myocardium from the posterior second heart field : implications for sinoatrial and atrioventricular mode development.. Vicente

21,22 Both populations can be integrated into one considering two phases of addition of cells to the arterial pole: an initial contribution which gives rise to the right

RhoA expression has been reduced in this stage to the sinus venosus myocardium including the myocardial sleeve surrounding the pulmonary vein, the right-sided SAN area, positive

On whole mount ISH Hcn4 expression was observed in HH11-12 embryos throughout the entire developing heart tube (Figure 6.3a-b) with a slightly more marked staining at the

Additional Hcn4 expression is observed at the base of the atrial septum, the putative AVN area, (Figure 7.3k, 7.3l) which expresses cTnI (Figure 7.3m) and shows a mosaic

The contribution at the arterial pole (anterior or secondary heart field) is of importance for the proper development of the outflow tract and the right ventricle, while the

In this thesis we have described the cellular contribution of second heart field-derived cells to the developing heart, focusing on the morphological and functional development of