Hepatitis C virus intracellular host interactions
Liefhebber, J.M.P.
Citation
Liefhebber, J. M. P. (2010, December 1). Hepatitis C virus intracellular host interactions. Retrieved from https://hdl.handle.net/1887/16189
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/16189
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Hepatitis C virus
intracellular host interactions
Colophon:
Cover: “Sleeping dragon” by J.M.P. Liefhebber Lay-out: C.J. Liefhebber
Print: Buijten & Schipperheijn Grafimedia, Amsterdam
Copyright© J.M.P.Liefhebber. All rights reserved. No part of this book may be reproduced or transmitted, in any form or by any means, without permission of the author.
Hepatitis C virus
intracellular host interactions
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op woensdag 1 december 2010
klokke 11.15 uur
door
Johanna Maaike Pieternella Liefhebber
geboren te Hagestein in 1981
Promotiecommissie
Promotor: prof. dr. W.J.M. Spaan Co-promotor: dr. H.C. van Leeuwen Overige leden: prof. dr. E.J. Snijder
prof. dr. F. Koning
prof. dr. P.J.M. Rottier, Universiteit Utrecht
Voor mijn ouders
“Wanneer je verstandig bent, vermeng je het ene ding met het andere:
Hoop niet zonder twijfel en twijfel niet zonder hoop.”
- Lucius Annaeus Seneca
Table of content
6
Table of content
7
Chapter 2
Table of contents
Page
Chapter 1 General introduction 9
Outline of thesis 28
Chapter 2 Hepatitis C virus NS4b carboxy-terminal domain is a membrane-binding domain
Virol J. 2009 May 25; 6: 62 43
Chapter 3 Characterization of Hepatitis C virus NS3 modifications in the context of replication
J Gen Virol. 2010 Apr; 91 (Pt4): 1013-8 69
Chapter 4 Isolation of Hepatitis C virus NS3 interacting proteins in
the context of replication 91
Chapter 5 The human collagen beta (1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum-localized protein
BMC Cell Biol. 2010 May 14;11:33 121
Chapter 6 Characterization of the interaction between Hepatitis C virus
NS3 and GLT25D1 143
Chapter 7 General discussion 159
English summary 191
Nederlandse samenvatting 195
Curriculum vitae 198
List of publications 199
