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University of Groningen Pharmacoeconomics of prophylactic, empirical, and diagnostic-based antibiotic treatments Purba, Abdul

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University of Groningen

Pharmacoeconomics of prophylactic, empirical, and diagnostic-based antibiotic treatments Purba, Abdul

DOI:

10.33612/diss.128518764

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Purba, A. (2020). Pharmacoeconomics of prophylactic, empirical, and diagnostic-based antibiotic

treatments: Focus on surgical site infection and hospitalized community-acquired pneumonia. University of Groningen. https://doi.org/10.33612/diss.128518764

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STELLINGEN

Behorende bij het proefschrift

Pharmacoeconomics of prophylactic, empirical, and diagnostic-based

antibiotic treatments: Focus on surgical site infection and hospitalized

community-acquired pneumonia

Abdul Khairul Rizki Purba

1. Use of prophylactic antibiotics for surgical site infections should take into account the local epidemiological data of the pathogens and antimicrobial susceptibility (This Thesis)

2. Empirical treatment of community acquired pneumonia should be guided by culture data and susceptibility testing both explicitly within the local context (This Thesis)

3. Together with additional consideration of culture findings and the Pneumonia Severity Index (PSI) assessment, a 3-day clinical assessment is essential to predict the prognosis of 14-day mortality for pneumonia patients (This Thesis) 4. Community healthcare centers, next to their essential role in resource-limited

settings in preventing further complications, could potentially serve as budget controllers by averting hospital infections and thus reducing inpatient costs (This Thesis)

5. Persons using penicillin treatments thoughtlessly are morally responsible for deaths of patients succumbing to infections with penicillin-resistant

organisms (after Sir Alexander Fleming)

6. Where clinicians are not confident in abstaining from prescribing antibiotics in non-life-threatening situations, a delayed antibiotics strategy may be an acceptable compromise in place of immediate prescribing as to still

significantly reduce (unnecessary) antibiotic use (after Spurling) 7. Success comes along with a positive spirit

8. What doesn’t kill you makes you stronger (Kelly Clarkson)

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