A study into genes encoding longevity in humans
Kuningas, M.
Citation
Kuningas, M. (2007, December 4). A study into genes encoding longevity in
humans. Retrieved from https://hdl.handle.net/1887/12474
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral
thesis in the Institutional Repository of the University
of Leiden
Downloaded from: https://hdl.handle.net/1887/12474
Note: To cite this publication please use the final published version (if
applicable).
153
Acknowledgements
I would like to acknowledge all the people who directly or indirectly have contributed to the results presented in this thesis. Especially I would like to thank all my colleagues at the depart- ment of Gerontology and Geriatrics in the Leiden University Medical Center for their help and support. Special thanks to the young researchers for the nice “bounty” breaks in the afternoons, which were always good reasons to flight from and to return to work again. I would also like to express my gratitude to all my friends, here and far, for the good moments we had and hopefully will have in the future.
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List of publications
Kuningas M, Mooijaart SP, van Heemst D, Zwaan BJ, Slagboom PE, Westendorp RGJ. Genes encod- ing longevity; from model organisms to man. Submitted for publication
Kuningas M, Mooijaart SP, Jolles J, Slagboom PE, Westendorp RGJ, van Heemst D. VDR gene vari- ants associate with cognitive function and depressive symptoms in old age. Neurobiolog y of ageing, in press
Kuningas M, Putters M, Westendorp RGJ, Slagboom PE, van Heemst D. SIRT1 gene, age-related dis- eases and mortality. The Leiden 85-plus Study. J Gerontol A Biol Sci Med Sci, 2007 Sep;62(9):960-596 Kuningas M, de Rijk RH, Westendorp RGJ, Jolles J, Slagboom PE, van Heemst D. Mental performance
in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors. Neuropsychopharmacolog y, 2007 Jun; 32(6):1295-301
Mooijaart SP, Kuningas M, Westendorp RGJ, Houwing-Duistermaat JJ, Slagboom PE, Rensen PCN, van Heemst D. The Liver X Receptor Alpha associates with human lifespan. J Gerontol A Biol Sci Med Sci, 2007 Apr; 62(4):343-9
Kuningas M, Mägi R, Westendorp RGJ, Slagboom PE, Remm M, van Heemst D. Haplotypes in the human FOXO1a and FOXO3a; impact on disease and mortality at old age. Eur J Hum Genet, 2007 Mar;15(3):294-301
Kuningas M, Mooijaart SP, Slagboom PE, Westendorp RGJ, van Heemst D. Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study.
Biogerontolog y, 2006 Aug; 7(4):231-8
Kuningas M, Slagboom PE, Westendorp RGJ, van Heemst D. Impact of genetic variations in the WRN gene on age related pathologies and mortality. Mech Ageing Dev., 2006 Mar;127(3):307-13
Mooijaart SP, Brandt BW, Baldal EA, Pijpe J, Kuningas M, Beekman M, Zwaan BJ, Slagboom PE, Westendorp RGJ, van Heemst D. C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age. Ageing Res Rev., 2005 Aug;4(3):351-71
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Curriculum vitae
Maris Kuningas was born on July 21, 1979 in Kuressaare, Estonia. She spent her childhood in Võhma, where she also went to school. After her graduation from the secondary school in 1997 she continued her education in Tartu University, Estonia, at the department of Biotechnol- ogy and Biomedicine. She obtained her Bachelor in Science (BSc) degree in Biotechnology and Biomedicine in 2001. At the same department she obtained her Masters’ in Science (MSc) degree in Molecular Biomedicine in 2003. From 2004 to 2007 she was a PhD student at the department of Gerontology and Geriatrics of the Leiden University Medical Center, The Netherlands. Since January 2007 she is employed as a PostDoc at the department of Gerontology and Geriatrics of the Leiden University Medical Center on the project “LifeSpan” (FP6 036894), which is an EU funded Network of Excellence that integrates research into development and ageing.