University of Groningen
Identification and evolution of a novel instructor gene of sex determination in the haplodiploid wasp Nasonia
Zou, Yuan
DOI:
10.33612/diss.134366133
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Zou, Y. (2020). Identification and evolution of a novel instructor gene of sex determination in the haplodiploid wasp Nasonia. University of Groningen. https://doi.org/10.33612/diss.134366133
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Propositions accompanying the PhD thesis:
Identification and evolution of a novel instructor gene of sex determination in haplodiploid wasp Nasonia
1. The gene name "wasp overruler of masculinization (wom)" indicates that Nasonia embryos have default male development. (this thesis)
2. The fact that wom is maternally silenced in haploid unfertilized eggs, constitutes the maternal control of Nasonia sex determination. (Verhulst et al. 2010; this thesis)
3. Because there are many ways to impede female-specific splicing of doublesex transcripts, the molecular identification of genetic male and female determiners for insects has proved to be challenging. (this thesis).
4. To avoid endless regression, the expression of wom must be initiated by maternally provided factors (this thesis).
5.The fact that wom is expressed in haploid unfertilized eggs of the gynandromorph strain HiCD12, reflects a loss of function and a loss of maternal control (this thesis).
6. Wom originated from a p53 homolog (p53-2) after incorporation of a partial duplication of its neighboring gene LOC100678853 before the emergence of the Nasonia-Trichomalopsis clade. The evolutionary origin of LOC100678853 is an enigma. (this thesis)
7. Ever tried. Ever failed. No matter. Try again. Fail better. (Samuel Beckett)
8. I don’t need a time. What I need is a deadline. (Duke Ellington)
9. If I had to choose between DNA and RNA, I would choose RNA because it has U in it.
