University of Groningen
Right ventricular function and pregnancy in congenital heart disease
Siegmund, Anne
DOI:
10.33612/diss.144690990
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2020
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Citation for published version (APA):
Siegmund, A. (2020). Right ventricular function and pregnancy in congenital heart disease. University of
Groningen. https://doi.org/10.33612/diss.144690990
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Right ventricular function and pregnancy
in congenital heart disease
Anne S. Siegmund
Right ventricular function and pregnancy in congenital heart disease
Financial support for the publication of this thesis by the following institutions and companies is gratefully acknowledged: University of Groningen, Graduate School of Medical Sciences, Groningen University for Drug Exploration (GUIDE), Noordnegentig, Medis Medical Imaging Systems bv, ChipSoft, Servier Nederland Farma B.V.
Cover design: Nine van der Wal Lay-out: Publiss | www.publiss.nl
Printing by: Ridderprint | www.ridderprint.nl
© Copyright: A.S. Siegmund ISBN : 978-94-6416-263-9
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Right ventricular function and pregnancy in congenital
heart disease
Proefschrift
ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. Cisca Wijmenga
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 25 november 2020 om 14:30 uur
door
Anne Suzan Siegmund
geboren op 19 mei 1993
te Zoetermeer
Promotores
Prof. dr. Dirk Jan van Veldhuisen
Prof. dr. Catherina M. Bilardo
Copromotores
Dr. Petronella G. Pieper
Dr. Michael G. Dickinson
Beoordelingscommissie
Prof. dr. Rudolf A. de Boer
Prof. dr. Basky Thilaganathan
Prof. dr. Werner Budts
Financial support by the Dutch Heart Foundation for the publication of this thesis is gratefully acknowledged.
Paranimfen
Drs. Bernadet T. Santema
Drs. Sebastiaan H.C. Klaassen
Content
Chapter 1 Introduction 9
Part I Pathophysiological mechanisms
Chapter 2 Uteroplacental Doppler flow and pregnancy outcome in women with Tetralogy of Fallot.
Ultrasound Obstet Gynecol. 2017 Feb;49(2):231-239
21
Chapter 3 Pregnancy in women with corrected aortic coarctation: uteroplacental Doppler flow and pregnancy outcome. Int J Cardiol. 2017 Dec 15;249:145-150.
43
Chapter 4 Maternal right ventricular function, uteroplacental circulation in first trimester and pregnancy outcome in women with congenital heart disease.
Ultrasound Obstet Gynecol. 2019 Sep;54(3):359-366.
63
Chapter 5 Reduced right ventricular function on cardiovascular magnetic resonance imaging is associated with uteroplacental impairment in Tetralogy of Fallot. J Cardiovasc Magn Reson. 2020 Jul 16;22(1):52-020-00645-9
83
Chapter 6 Abnormal venous hemodynamics in pregnant women with Tetralogy of Fallot: A case series.
In preparation
101
Chapter 7 Cardiovascular determinants of impaired placental function in women with cardiac dysfunction Submitted
Part II Clinical factors
Chapter 8 Early N-terminal pro-B-type natriuretic peptide is associated with cardiac complications and function during pregnancy in congenital heart disease. Submitted
135
Chapter 9 Doppler gradients, valve area and ventricular function in pregnant women with aortic or pulmonary valve disease: left versus right.
Int J Cardiol. 2020 May 1;306:152-157.
151
Chapter 10 Summary, discussion and future perspectives 169
Appendices I Dutch summary | Nederlandse samenvatting II Acknowledgements | Dankwoord
III List of publications IV About the author
182 184 189 191
