Regulation and subversion of HPV16-specific immunity in cancer patients Piersma, S.J.

Pieters aan het Instute for Risk Assessment Sciences (IRAS) van de Universiteit Utrecht, werd zij in 2000 voor een jaar gekozen tot student-bestuurslid van de faculteit

Human papilloma virus specific T cells infiltrating cervical cancer and draining lymph nodes show remarkably frequent use of HLA- DQ and –DP as a Restriction Element | 34.

Since we found that FOXP3+ T cells had a negative effect on the prognosis of cervical cancer patients, we investigated whether the HPV-specific tumor

Thus, evaluation of cervical cancer patients with respect to their lymph node status revealed that the LN - patient group, which in general has a good prognosis, displays

In 4 cases the LNMC responded to HPV16 and in 1 patient an HPV18 response was detected by proliferation and IFNg production (Table 1, Figure 4A). Similar to the TIL

Figure 5 vd Burg et al. TIL cultures from cancer patients contain HPV- specific regulatory CD4+ T cells. A) The proliferative reacti- vity of HPV-specific CD4+ T cell lines derived

All patients displayed an HPV16- specific T-cell response after vaccination (Figure 1). In 5 of the 6 patients HPV16 E6-specific IFNγ-producing T cells were already

The absence of a HPV16- specific immune response in patients with HSIL and the presence of such responses in about half of the patients with cancer previously led us to