VU Research Portal
Loss-of-function shRNA screens to identify mechanisms of PARP inhibitor resistance in BRCA1-mutated mouse mammary tumors
Xu, G.
2016
document version
Publisher's PDF, also known as Version of record
Link to publication in VU Research Portal
citation for published version (APA)
Xu, G. (2016). Loss-of-function shRNA screens to identify mechanisms of PARP inhibitor resistance in
BRCA1-mutated mouse mammary tumors.
General rights
Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain
• You may freely distribute the URL identifying the publication in the public portal ? Take down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
E-mail address:
vuresearchportal.ub@vu.nl
208
PHD PORTFOLIO
Name PhD student: Guotai Xu PhD period: 2009.10.13-2016.01.05
Name PhD supervisors: Prof. dr. Sven Rottenberg and Prof. dr. Piet Borst Name PhD promotors: Prof. dr. Hein te Riele and Prof. dr. Sven Rottenberg
I PhD training
Attended Courses
Radiotherapy introduction course
Radiation protection course
Laboratory animal course, Utrecht, 2010
OOA course “Noncoding RNAs and Cancer”, NKI, 2010
Course “Next Generation Sequencing”, LUMC, 2011
OOA course “Preclinical assays” NKI, 2012
OOA course” Histopathology of tumors”, Vumc, January 30-31, 2013
OOA course “The Macroscopic, Microscopic and Pathologic Anatomy of the House Mouse”, AMC, April 8 - 11, 2013
OOA course “Basic Medical Statistics”, NKI, Nov 22, November 25 -29, 2013
OOA course “Replication stress and chromosomal instability”, NKI, AMC and VUMC, January 6-10, 2014
MGC-OOA course “Transgenesis, gene targeting and in vivo imaging”, LUMC, June 8-12, 2015
Attended Meetings
“AACR Translational Cancer Medicine”, Amsterdam, Mar 21-24, 2010
“OOA PhD students retreat”, poster presentation, Texel, 2010
“Responses to DNA damage: From Molecular mechanism to human disease”, Egmond, The Netherlands, April 3-8, 2011
“OOA PhD students retreat”, oral presentation, Texel, 2011
“OOA PhD students retreat”, oral presentation, Ermelo, 2012
102 AACR annual meeting, poster presentation, Chicago, Mar 31- Apr 4, 2012
209
“Current state-of-the-art of Proteomics in the Netherlands”, Amsterdam, Nov 30, 2012
Keystone Symposia: Joint meeting on “DNA replication and
Recombination (X5)” and “Genomic Instability and DNA repair”, poster presentation, Banff, Canada, March 3-8, 2013
“OOA PhD students retreat”, Zeeland, oral presentation, Oct 23 –Oct 25, 2013
7th International PhD Student Cancer Conference, oral presentation, London Research Institute, London, June 19-21, 2013
7th Workshop on Innovative Mouse Models, poster presentation, Leiden, The Netherlands, 2013
International Symposium on “The promise of PARP inhibitors for Personalized Cancer Treatment”, Amsterdam, 2015
105 AACR annual meeting, Philadelphia, Apr 18- Apr 22, 2015
II Teaching
Bachelor student: Stephan Freriks, 2011
Project: Expression analysis of genes that may cause olaparib resistance in Brca1-/-;p53-/- mouse mammary tumors
Current position: Technician in Prof. dr. Sven Rottenberg’s group at NKI
Master student (co-supervised with Prof. dr. Sven Rottenberg): Bharath Kumar Sampadi, 2011-2012
Project: Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance
Current position: PhD student in Leiden University
Master student: Chenwei Hu, 2012
Project: Loss of Helb causes PARP inhibitor resistance in BRCA1; p53-deficient mouse mammary tumor cells
