Inflammation as a target for treatment in hand osteoarthritis

DE FACTORANALYSE. De factoranalyse is een methode om zonder veronderstellingen deelaspecten van een probleem te bestuderen. Op een geheel objectieve wijze wordt

2) To investigate the role of inflammation as a treatment target in hand osteoarthritis; and 3) To facilitate development of new treatment options by improving outcome

Symptomatic hand OA patients from the Hand Osteoarthritis in Secondary Care (HOSTAS) cohort completed questionnaires (demographics, MHQ, Australian/Canadian Hand Osteoarthritis

Methods: Radiographs of 262 RA patients (mean age 52 years, 66% women) from the BeSt study were scored for osteophytes in distal and proximal interphalangeal joints (DIPJ/PIPJ)

ACR,American College of Rheumatology; AUSCAN, Australian/Canadian Hand Osteoarthritis Index; CCT, clinical controlled trials; CMC, first carpometacarpal; CO, cross-over trial;

Two things are important considering tumor specific HSP90 inhibition effects: tumor cells are more dependent on HSP90 and HSP90 inhibitors have a greater affinity to tumor cell

Expression of the TNF superfamily cytokines is the greatest in renal tubular epithelial cells and to some extent podocytes, and is linked to tubular atrophy and interstitial

As the ATG4 protease family has been linked to a number of pathologies, and because its activity is essential and highly specific towards autophagy, the regulation of its