Regulation of the Ets transcription factor Tel
Roukens, M.G.
Citation
Roukens, M. G. (2010, April 15). Regulation of the Ets transcription factor Tel. Retrieved from https://hdl.handle.net/1887/15226
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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Curriculum Vitae
Mark Guido (Guy) Roukens was born on the 10th of October 1979 in Bleiswijk, the Netherlands. After graduating from the Stedelijk Gymnasium Schiedam in 1997 he studied Pharmaceutical Sciences at the University of Utrecht. From August 2001 until March 2002 he did a research internship at the lab of Dr. Miklos Toth at the Medical School of Cornell University in New York City in the United States. The internship stimulated his interest in molecular biology. Therefore, after obtaining a Master degree, in pharmaceutical sciences in 2003 and a pharmacist degree in 2004, he decided to change field; from September 2004 he started his PhD training in molecular and cell biology under supervision of Dr. David Baker. After a brief period as a postdoc in the same lab he will start working as a postdoc in the lab of Prof. Dr. Stefan Schulte-Merker at the Hubrecht Institute in Utrecht in April 2010.
Appendix: List of abbreviations
Crm1 = Chromosome Region Maintenance 1 (Exportin 1) DJNK = Drosophila Jun N-terminal Kinase
ECM = Extracellular Matrix EGF = Epidermal Growth Factor Elk-1 = Ets Like transcription factor 1 ERK = Extracellular signal Regulated Kinase ES cells = Embryonic Stem cells
Ets = E26 translocation specific FGF = Fibroblast Growth Factor
Fli-1 = Friend Leukemia virus integration 1 GABP = Growth Associated Binding Protein HAT = Histone Acetyl Transferase HDAC = histone deacetylase HSC = Haematopoietic Stem cells L(3)MBT = lethal(3)malignant brain tumor Mae = Modulator of the Activity of Ets MAPK = Mitogen Activated Protein Kinase MMP3 = Matrix Metallo Proteinase 3 mSIN3A = mammalian orthologue of Sin3 A NCOR = Nuclear Corepressor
PDGFRȕ = platelet derived growth factor receptor ȕ PU.1 = Purine Rich box 1
RTK = Receptor Tyrosine Kinase SAM = Sterile Alpha Motif SAP-1 = SRF Accessory Protein 1
SMRT = silencing mediator of retinoid and thyroid hormone receptors Su(H) = Suppressor of Hairless
SUMO = Small Ubiquitin-like Modifier Tel = Translocation Ets Leukemia
TIP 60 = 60 kDa trans-acting regulatory protein of HIV type 1 (Tat)-interacting protein
UBC9 = Ubiquitin Conjugating Enzyme 9 VEGF = Vascular Endothelial Growth Factor v-Src = Viral Sarcoma
