Characterization of embryonic stem cell
transplantation immunobiology using molecular imaging
Swijnenburg, R.J.
Citation
Swijnenburg, R. J. (2009, April 21). Characterization of embryonic stem cell transplantation immunobiology using molecular imaging. Retrieved from
https://hdl.handle.net/1887/13743
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STELLINGEN
Behorend bij het proefschrift
“Characterization of Embryonic Stem Cell Transplantation Immunobiology using Molecular Imaging”
1. Embryonic stem cells are not immune-privileged. (this thesis)
2. Immunogenicity of embryonic stem cells increases upon differentiation.
(this thesis)
3. In vivo bioluminescent imaging is a sensitive tool to non-invasively quantify embryonic stem cell transplantation survival and rejection. (this thesis) 4. Significant therapeutic benefit of mononuclear bone marrow cell therapy for
acute myocardial infarction is hampered by acute donor cell death. (this thesis) 5. A major challenge facing embryonic stem cell therapy is purification of
differentiated progeny to preclude tumor formation.
6. Supporting embryonic stem cell research is a pro-life position, since therapy using these cells will potentially be life-saving.
7. Adult stem cells do not transdifferentiate across tissue lineage boundaries.
(Irving Weissman, Cell 2004 Mar 5;116(5):639-48)
8. At this moment, the full promise of stem cell research remains unknown and should not be overstated. But […] these tiny cells may have the potential to help us understand, and possibly cure, some of the most devastating diseases and conditions. (Barack Obama, March 2009)
9. Chance favors the prepared mind. (Louis Pasteur) 10. Knowledge of basic science makes a curious clinician.
11. Surgeons are like embryonic stem cells; their clinical significance depends on differentiation.
12. If drug blood levels were to be rewarded, Barry Bonds could have won the Tour the France.
