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University of Groningen Characterization of Different Patient Populations with Atrial Fibrillation Kloosterman, Mariëlle

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University of Groningen

Characterization of Different Patient Populations with Atrial Fibrillation

Kloosterman, Mariëlle

DOI:

10.33612/diss.143841478

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Kloosterman, M. (2020). Characterization of Different Patient Populations with Atrial Fibrillation. University of Groningen. https://doi.org/10.33612/diss.143841478

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Stellingen

Behorende bij het proefschrift

Characterization of Different Patient Populations with Atrial Fibrillation

Door: Mariëlle Kloosterman

1. AF without risk factors (traditional-, less-established-, or subclinical-) is extremely rare. Recognition and management of AF risk factors is paramount – This thesis

2. Sex differences in outcome and quality of life are partially driven by the higher risk factor burden in women than in men – This thesis

3. Catheter ablation seems as safe in women as in men and should not be withheld from women with paroxysmal or persistent AF – This thesis

4. Quality of life is significantly lower in women with AF than in men with AF, especially in the physical domains. This is an important parameter that should not be underestimated. – This thesis

5. There is, at least, a partial genetic basis for AF in patients with heart failure – This

thesis

6. The disparity in blood biomarker profiles of patients with AF and concomitant heart failure with preserved versus reduced ejection fraction underscores the hypothesis that differences exist in the pathophysiological mechanisms that underlie AF in these heart failure phenotypes – This thesis

7. AF is a multifaceted, complex disease. Awareness of (sex)differences in patient- and disease characteristics, and incorporation of these differences into care and research, is warranted to address remaining lacunas in our knowledge – This thesis

8. Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less – Marie Curie

9. The real voyage of discovery consists not in seeking new landscapes, but in having new eyes – Marcel Proust

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