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University of Groningen Exploitation of macrocyclic chemical space by multicomponent reaction (MCR) and their applications in medicinal chemistry Abdelraheem, Eman Mahmoud Mohamed

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University of Groningen

Exploitation of macrocyclic chemical space by multicomponent reaction (MCR) and their

applications in medicinal chemistry

Abdelraheem, Eman Mahmoud Mohamed

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Abdelraheem, E. M. M. (2018). Exploitation of macrocyclic chemical space by multicomponent reaction (MCR) and their applications in medicinal chemistry. Rijksuniversiteit Groningen.

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

(2)

Propositions

Belonging to the thesis

Exploitation of Macrocyclic Chemical Space by Multicomponent

Reaction (MCR) and their Applications in Medicinal Chemistry

By

Eman M. M. Abdelraheem

1. Macrocycles are magic. [This thesis]

2. Multicomponent reaction (MCR) technology is a promising synthetic technology

to discover this magic. [This thesis]

3. Artificial macrocycles are an emerging and largely underexploited part of chemical space where potentially drugs for difficult genomic targets can be discovered. [This thesis]

4. Optimism, optimization and parenting are what make the difference between the

problem and the challenge. [my view]

5. With the macrocycle synthesis, you should be patient and sharp like a falcon. [my view]

6. If we know what it was we were doing, it would not be called research, would it?

[Albert Einstein]

7. Learn from yesterday, live for today, hope for tomorrow. The important thing is

to not stop questioning [Albert Einstein]

8. Your positive action combined with positive thinking results in success. [Shiv khera]

9. Success is no accident. It is hard work, perseverance, learning, studying, sacrifice and most of all, love of what you are doing or learning to do. [Pele]

10. Every time when I publish a paper, I thank my God and ask him to give me more.

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