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Pharmaceutical, chronobiological and clinical aspects of melatonin
Nagtegaal, J.E.
Publication date
2001
Link to publication
Citation for published version (APA):
Nagtegaal, J. E. (2001). Pharmaceutical, chronobiological and clinical aspects of melatonin.
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Contents s
PARTT 1 PHYSIOLOGICAL AND PHARMACOLOGICAL ASPECTS OF
MELATONINN 1 1.11 An overview of the physiological and pharmacological effects of melatonin 3
1.22 Light and dark control of the melatonin synthesis 12
1.33 Effects of exogenous melatonin 19 1.44 Side effects of melatonin 33 1.55 Further reading in this thesis 37 1.66 Future study on endogenous and exogenous melatonin 38
PARTT 2 PHARMACEUTICAL ASPECTS OF MELATONIN 51
2.11 Melatonin: drugs 'not for human use' 53 2.22 Melatonin: a survey of suspected adverse drug reactions 62
2.33 Correlation between concentrations of melatonin in saliva and serum in
patientss with delayed sleep phase syndrome 66
PARTT 3 CHRONOBIOLOGICAL ASPECTS OF MELATONIN 71 3.11 Delayed sleep phase syndrome: a placebo-controlled cross-over study on the
effectss of melatonin administered 5 hours before the individual dim light
melatoninn onset 73 3.22 The effect of melatonin administration on sleep, daytime sleepiness and
PARTT 4 CLINICAL ASPECTS OF MELATONIN 113 4.11 Effects of melatonin on the quality of life in patients with delayed sleep
phasee syndrome 115 4.22 Melatonin-responsive headache in delayed sleep phase syndrome:
preliminaryy observations 129 4.33 Traumatic brain injury-associated delayed sleep phase syndrome 141
PARTT 5 SUMMARY 149 5.11 Summary, general discussion and directions for future research 151
5.22 Samenvatting, algemene discussie en mogelijkheden voor toekomstig
onderzoekk 161 5.33 Curriculum Vitae 173 5.44 Publications 175
