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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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Recognizing axial spondyloarthritis

de Boer, J.J.H.

Publication date

2018

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Citation for published version (APA):

de Boer, J. J. H. (2018). Recognizing axial spondyloarthritis.

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Recognizing axial spondyloarthritis

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RECOGNIZING AXIAL SPONDYLOARTHRITIS

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RECOGNIZING AXIAL SPONDYLOARTHRITIS © J.J.H. de Winter, 2018.

All rights reserved. No part of this thesis may be reproduced in any form or by any means without permission of the auhtor.

ISBN 978-94-6332-425-0

Cover Johannes Rustenburg, Loes Kema Layout Loes Kema

Printed by GVO drukkers & vormgevers, Ede, NL

The background image at the start of each chapter is a radiograph of a symptomless participant of the Pre-SpA cohort, showing cervical syndesmophytes suggestive of SpA.

Printing of this thesis is financially supported by the Dutch Arthritis Foundation, AMC-UvA, ChipSoft and UCB Pharma.

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RECOGNIZING AXIAL SPONDYLOARTHRITIS

ACADEMISCH PROEFSCHRIFT ter verkrijging van de graad van doctor

aan de Universiteit van Amsterdam op gezag van de Rector Magnificus

prof. dr. ir. K.I.J. Maex

ten overstaan van een door het College voor Promoties ingestelde commissie, in het openbaar te verdedigen in de Aula der Universiteit

op vrijdag 23 november 2018, te 11:00 uur door Janna Johanna Hendrika de Boer

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Promotiecommissie

Promotores

Prof. dr. D.L.P Baeten AMC-UvA Prof. dr. R.B.M. Landewé AMC-UvA

Copromotor

Dr. M.G.H. van de Sande AMC-UvA

Overige leden

Prof. dr. J.M. van Laar Universiteit Utrecht Prof. dr. M. Maas AMC-UvA

Dr. S. Ramiro Universiteit Leiden Prof. dr. D. van Schaardenburg AMC-UvA

Prof. dr. P.I. Spuls AMC-UvA Faculteit der Geneeskunde

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CONTENTS Chapter 1 Part I Chapter 2 Chapter 3 Part II Chapter 4 Chapter 5 Chapter 6 Part III Chapter 7 Chapter 8 Chapter 9 Appendices 7 17 19 35 59 61 75 91 107 109 131 141 157 165 167 169 171 General introduction and outline

Recognizing the disease burden of axial spondyloarthritis

Peripheral disease contributes significantly to the disease burden in axial spondyloarthritis

Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis

Rocognizing the diagnosis of axial spondyloarthritis

Magnetic Resonance Imaging of the Sacroiliac Joints Indicating Sacroiliitis According to the Assessment of SpondyloArthritis international Society Definition in Healthy Individuals, Runners, and Women With Postpartum Back Pain

Anti-CD74 antibodies have no diagnostic value in early axial spondyloarthritis: data from the SPondyloArthritis Caught Early (SPACE) cohort

Absence of HLA-C*07 is associated with susceptibility to axial spondyloarthritis

Recognizing the preclinical phases of axial spondyloarthritis

Clinical and imaging signs of spondyloarthritis in first degree relatives of HLA-B27 positive ankylosing

spondylitis patients: the pre-spondyloarthritis (Pre-SpA) cohort

First-degree relatives of axial spondyloarthritis patients of the Pre-SpA cohort would consider using medication in a preventive setting

General discussion and summary Nederlandse samenvatting Curriculum vitae

PhD portfolio List of publications Dankwoord

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