University of Groningen
New Biocatalytic Approaches for Alcohol Oxidations and Ketone Reductions Using
(Deaza)Flavoenzymes
Martin, Caterina
DOI:
10.33612/diss.145245371
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Martin, C. (2020). New Biocatalytic Approaches for Alcohol Oxidations and Ketone Reductions Using (Deaza)Flavoenzymes. University of Groningen. https://doi.org/10.33612/diss.145245371
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1
Propositions
Accompanying the thesis
New Biocatalytic Approaches for Alcohol Oxidations and Ketone Reductions Using (Deaza)Flavoenzymes
By Caterina Martin
1. For a biochemist, one of the most valuable features of flavin-containing enzymes is their yellow colour.
2. The design of a thoughtful molecular biology approach can allow to save time and resources. (Chapter 2)
3. Advertisement from different companies have created the false illusion that yeast expression of heterologous proteins through protein secretion easily allows high yields (above 800 mg/mL of colture), but it is not so competitive in regards to E.coli when talking about bacterial proteins. (Chapter 3)
4. The informative value of steady-state kinetic parameters is overrated when studying an enzyme as biocatalyst: the same importance should be given to enzyme performance by analyzing e.g. conversion yields over time and with different temperatures.
5. More acknowledgment should be given to academic research because industrial research sometimes would not dare to undertake projects with a high risk of failure, even if they could lead to relevant discoveries.
6. We are selfish by nature, every decision that we take is instinctively based on the assumption that it will provide some benefit to us, to be altruistic we should be more foresighted.
