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The handle http://hdl.handle.net/1887/48877 holds various files of this Leiden University dissertation
Author: Li, Y.
Title: A new method to reconstruct the structure from crystal images Issue Date: 2017-05-03
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Curriculum Vitae
Yaowang Li was born on September 1, 1983 in Jiangxi, China. He started his Food Science and Engineer education in Jiangxi Agricultural University in 2004. During the college time, his interest focus on the computer science. In 2008, He obtained a bachelor degree in Food Science.
At the same year, He decided to join the Postgraduate Admission Test, and it was lucky that his Master’s supervisor provide him a project about bioinformatics research at China Argicultural University.
Through data analysis with statistical methods, to build the connection between structure and activity for antioxidative peptide.
Shortly after he received a master degree, in 2011, he got the schol- arship from China Scholarship Council and joined the project in the department of Biophysical Structural Chemistry, Leiden University, as a PhD candidate. He devoted himself to the research of new methods that can solve the structure of macromolecules base on randomly oriented projections of three-dimensional nano-crystals, which was reported in this thesis.
Currently he will join the Beijing Advanced Innovation Center For Structural Biology at Tsinghua University, continue to the methods re- search in structural biology.
Publications
1. van Genderen E.*, LI Y.W.*, Nederlof I., Abrahams,J.P. (2016) Lattice filter for processing image data of three-dimensional protein nanocrys- tals, Acta Crystallographica Section D: Biological Crystallography, vol 72, pp. 34-39. (* co-first author)
2. Abrahams J, van Genderen E, Nederlof I, Clabbers M, Li Y (2015) Electron diffraction and imaging of 3D nanocrystals of pharmaceuticals, peptides and proteins. Acta Crystallographica Section A: Foundations and Advances 71, pp. s103.
3. Clabbers Max TB, van Genderen E, Nederlof I, Li Y, Abrahams J (2015) Electron crystallography of 3D nano-crystals. Acta Crystallographica Section A: Foundations and Advances 71, pp. s405.
4. Nederlof, I, Li, Y.W., van Heel, M., Abrahams, J.P., (2013) Imaging protein three-dimensional nanocrystals with cryo-EM, Acta Crystallo- graphica Section D: Biological Crystallography, vol. 69, pp. 852-859.
5. Nederlof, I, van Genderen, E., Li, Y.W., Abrahams, J.P., (2013) A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals, Acta Crystallographica Section D: Biological Crystallography, 69, pp. 1223- 1230.
6. Li Y.W., Li B., (2013) Characterization of structure-antioxidant activ- ity relationship of peptides in free radical systems using QSAR models:
key sequence positions and their amino acid properties. Journal of The- oretical Biology, 318, pp. 29-43.
7. Li Y.W., Li B., He J., Qian P., (2011) Quantitative structure-activity re- lationship study of antioxidant peptides by using different sets of amino acids descriptors. Journal of Molecular Structure, 998, pp. 53-61.
8. Li Y.W., Li B., He J., Qian P.,(2011) Structure-activity relation- ship study of antioxidative peptides by QSAR modeling: the amino acid next to C-terminal affects the activity. Journal of peptide science,17(6),pp.454-462.
9. Li Y.W., Li B., (2010) Quantitative structure-activity relationship study of radical scavenging peptides based on ORAC method by using differ- ent sets of amino acids descriptor. International Conference of CMBB (Cellular, Molecular Biology, Biophysics and Bioengineering), vol. III, IEEE press, pp. 251-257.
