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University of Groningen Social stress: the good, the bad, and the neurotrophic factor Lima Giacobbo, Bruno

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University of Groningen

Social stress: the good, the bad, and the neurotrophic factor

Lima Giacobbo, Bruno

DOI:

10.33612/diss.98795800

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Lima Giacobbo, B. (2019). Social stress: the good, the bad, and the neurotrophic factor: understanding the brain through PET imaging and molecular biology. University of Groningen.

https://doi.org/10.33612/diss.98795800

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Propositions

1.Neurotrophins are not a biomarker for one specific brain disease, however, these proteins shed some light on the pathophysiology of all brain diseases (Chapter 2);

2.The consequences sociability have on health quality cannot be underestimated, as it can be an important ally – or a dangerous foe – in the fight against diseases (Chapter 3);

3.Although TSPO activation plays a major role in PET imaging of neuroinflammation, it is but a part of the whole process of inflammation (Chapter 4);

4.Understanding how neuroinflammation is associated with depressive-like behavior might allow us another way to treat depression (Chapter 5);

5.Future studies using resident/intruder paradigms need to carefully address its protocol, as either resident, intruder, and paradigm, play an equal role in the paradigm (Chapter 6);

6.PET imaging of brain inflammation needs severely the development of new radiotracers that can be used in research and further implemented in clinical settings (Chapter 5);

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Social stress: the good, the bad, and the neurotrophic factor Lima Giacobbo,