Novel thyroid specific transcripts identified by SAGE: implication for congenital hypothyroidism - Appendix: nucleotide and amino acid sequences

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Novel thyroid specific transcripts identified by SAGE: implication for congenital

hypothyroidism

Moreno Navarro, J.C.

Publication date

2003

Link to publication

Citation for published version (APA):

Moreno Navarro, J. C. (2003). Novel thyroid specific transcripts identified by SAGE:

implication for congenital hypothyroidism.

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Appendix:: nucleotide and amino acid sequences

Appendix:: nucleotide and amino acid sequences

b b

-: : :: :GGCATTCTCC P . : : : : : : : ii . . M Y F L T P I L V A I L C C rTTTGGTTGTGTGGJJ ! II L V V W I F K N A 1 M I K :: ". :GAAGCTCC ;GATGAAGAC P V- : it II R A E A R P W V D E D L K D S 1 6 11 ^GATGCTGATGAAl ! LL ': 2 A E D A I : E E N E H ] : 2 2 1 1 . . .. .. v ; - _ E p Y EE L L N K R R S V R F I S N E Q V P M E lACAGCC ' :.' v ' / -VV I D N V I R T A G T A P S G A H T E P WW T F V V V K D P D V K H K I R K I I E EE E E E 1 N Y M K R M G H R W V T D L K KK L F. T M W I K E Y L D T A P I L ï L I FF K Q V H G F A A N G K K K V H Y Y N E II 3 V S I A C G I L L A A L Q N A G L V TT V T T T P L N C G P R L R V L L G R P ;;_" :_{. - :} ₃₂ AA H E K L L M L L P V G Y P S K E A T V 2 7 2 ... . . . . . . PP D L K R K P L D Q I M V T V .... .'. ... . . . . . . .. . . . . . . . . . . . .. . .. - - ; ; l : . . . - : : . .. AAAAGTATTA .. . . \J rTGGTTATAATC .. p Chap.Chap. 4, fig. 1b 155 5

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AA . \ . . . ; "

:•:: v : : ? : i v A i L c

rcTG:: • • • . . • • A C A G A ;

-:: • V / W I F K N A D F K AGAACC?? AAGC1 ATGAAG:

AA A F .-. D E I :' •• • - • . . . E D AA E W Q : - " : P F S H K H Y P E K E MM K R 5 E » F - ï EE L L N K R R S v R F I S N E Q V P M E •• • • VV I D N V I R T A G T A ? 3 G A H T E F •• • • W T F V V V K D P D V K H K I R K I I E E EE E E E I N Y M K R M G H R W V T D L K AACC : .' . . . K L R T N W I K Ï Y I ,, D T A P I L I L I FF K Q V H G F A A N G K K K V H Y Y N E -- - - - ; • Ï , : • • : . . /..:_-?: VGGTAAATAATGGAATC? I S V S I A C G II L L A A L Q : : . ATCAGAC11 • ' ' ' "• •' • • ; - . . • :: S .. : . . . . . . • . . - . ' .. P E F D C I • . • ' . . . . : .. • •_ . • • - rGGG ACATGAA ;.. L W I ~ T E A P P R T ' .. . ' . - . : : . : : . ; ; • AAA : :AAA !TG ' . . . _ . . . •• IGCCCCTGCTTTTC rGAGCCTC ] TCTTG : .. . f : ;---.--;---.-- --:-~z~:-. AAAAGTATTA A

-.-.-.:;-. ;- ;AA : " ; : : ; ; . . ; . \ . re ": . A : A A T :T rGi : A T A T :S AT I A T T T ;AP : •• •• AGTTTAGAATGTTTAA; '• '' " " -" - - •

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Appendix:: nucleotide and amino acid sequences GGCC GGCC ATGATG . : " : _ _ M A S L G L L L L L L L T A L P P L W S S ii I A AC1 ACCATTGCA : T G A 7 C C J SS S L P L C E K A [ A D L I L AA A A :CGTCTTC II ] L E A I ' F L E Q R L P E I N L l ;CATGG]] - AA ;AC :; \ AA i A AA rc-GG GG :•: :- v R V L E E 2 L K S V :• i .-. A 24]] " A :i .. • • :i . i AA. ;CTGGGGGA AA :TGGA

22 E P L L C L S L R M E K L E :: . 3CI ATCCAGAGATC

1011 A A 2 F L H Y L K L S E K Y L F 1.

3 6 ]] TTCCAGCTGA i AGCCCG ["TTTG A A FC iATC 'A 'A A \ .

FF Q L T L Q i F W K L H A W I K T I 14 0 :: : : A ' 'A : G T T C :- : c A A A . . . ! A . A. AA - A. : 4? 1 4 11 A S L V Y P T F G P Q D S F S E E R S D GTGTGC RGGTGCA I : A A- A IAG T C A VV | L V Q L A- :• A A .-. ; 1 S 1 8 0 :--:-- : A A A :A A A 6 0 0 1 8 11 C M K C S G Y C . 2 0 0 ÉÉ 1 C T G C T C T 1 A RCC AGGGACCJ • •• - 6 6 0 L L F F L W A R M R G | T CC 2 2 0 ,, . 1 :. . - • i a : :. :. 72 0 2211 Q D Y : N I F | A N M :•: D I N R R A E A •• A A A ; i . :A: • i A A A A. 2411 : A J . D F M E N M F G M 260 7 8 11 G G C G G C T T : ; I C G A C T I A A A. A I . 8 4 0 FF A -•• L R W L E A I L S .-. 2 K 2 8 0 8 4 11 A A ATGC1 I G G A G C C T G A T G ' ; " A : A A AA A A . QQ Q E G A E P D A E D E E L S K A I : .

9 0 11 AGGAGA AA A AAAAA A . - ATGGC 9 6 0 3 0 11 2 Q Q H I A F :• -• F R E K Q F P D G : TG A " ::c A A I A ; i :TTCCTATA :ATCCTG C S S K N T A T A V A A LL L Y I L A 1 0 6 11 -; - ; - •"• ; :AG : AA E Y E A :: R E ? H - S T P P P P S S 3 6 0 ;; A : CCAGCXGCCT A AA . \ ' . \1 A. A !C A A ]] . AAA ' ' . A ' AAA. . . A. A iCCCTGAGTA ' ."- I ' " L22 6 1 ' I AA a . ; A A AAA i

'-Chap.Chap. 5, fig. 1b

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