Inclusion body myositis : a nationwide study Badrising, U.A.

(1)

Inclusion body myositis : a nationwide study

Badrising, U.A.

Citation

Badrising, U. A. (2006, September 20). Inclusion body myositis : a nationwide study.

Retrieved from https://hdl.handle.net/1887/4567

Version:

Corrected Publisher’s Version

License:

Licence agreement concerning inclusion of doctoral thesis in the

_{Institutional Repository of the University of Leiden}

Downloaded from:

https://hdl.handle.net/1887/4567

(2)

Inclusion Body Myositis

A na tionw ide study

(3)

ISBN-10: 90-6464-031-9 ISBN-13: 97 8 -90-6464-031-5

D e s ig n e d b y : G r a fi s c h Bu r e a u C h r is tin e v a n d e r V e n , V o o r s c h o te n P r in te d b y : G r a fi s c h e P r o d u c tie s , U n iv e r s ita ir F a c ilita ir Be d r ijf, L e id e n © U .A . Ba d r is in g , 2 006

(4)

Inclusion Body Myositis

A nationwide study

PROEFSCHRIFT ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gez ag van de R ector M agnificus Dr. D.D. Breimer,

hoogleraar in de faculteit der W iskunde en Natuurwetenschappen en die der Geneeskunde,

volgens besluit van het College voor Promoties

te verdedigen op woensdag 20 september 2006 klokke 13.45 uur

door

Umesh Arvind Badrising

(5)

P

R O M O T I E C O M M I S S I E

Promotor

Prof. dr. A.R. Wintzen Co-p romotore s

Dr. J.J.G.M. Verschuuren Dr. M.L.C. Maat-Schieman Re f e re n t

Prof. dr. B.G.M. van E ngelen (Radboud Universiteit Nijmegen) L id

(6)

C

ON TEN TS

CH A P T E R I General introduction

CH A P T E R I I Epidemiology of inclusion body myositis in the Netherlands:

A nationwide study

CH A P T E R I I I Inclusion body myositis: Clinical features and clinical course of the

disease in 64 patients

CH A P T E R I V Muscle weakness in inclusion body myositis is not aggravated due

to synaptic dysfunction.

CH A P T E R V Associations with autoimmune disorders and H LA class I and II

antigens in inclusion body myositis

CH A P T E R V I Comparison of weakness progression in inclusion body myositis

during treatment with methotrex ate or placebo

CH A P T E R V I I Summary and discussion

(7)