Diagnosis, transmission and immunology of human Oesophagostomum bifurcum and hookworm infections in Togo

Diagnosis, transmission and immunology of human

Oesophagostomum bifurcum and hookworm infections in

Togo

Pit, D.S.S.

Citation

Pit, D. S. S. (2000, October 12). Diagnosis, transmission and immunology of human Oesophagostomum bifurcum and hookworm infections in Togo. Retrieved from https://hdl.handle.net/1887/13934

Version: Corrected Publisher’s Version

License:

Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the

University of Leiden

Downloaded from: https://hdl.handle.net/1887/13934

Diagnosis, transmission and immunology of

human Oesophagostomum bifurcum and

Diagnosis, transmission and immunology of human

Oesophagostomum bifurcum and hookworm infections in Togo

PROEFSCHRIFT

ter verkrijging van de graad van Doctor aan de Universiteit te Leiden,

op gezag van de Rector Magnificus Dr. W.A. Wagenaar, hoogleraar in de faculteit der Sociale Wetenschappen,

volgens besluit van het College voor Promoties te verdedigen op donderdag 12 oktober 2000

te klokke 14.15 uur

door

Promotie commissie

Promotor: Prof. Dr. A.M. Deelder Co-promotor: Dr. A.M. Polderman Referent: Prof. Dr. J. Vercruysse

(Universiteit van Gent, België) Overige leden : Prof. Dr. P.C. Stuiver

Prof. Dr. H. Goossens Prof. Dr. J.M. Wit

Dr. P. Magnussen (Danish Bilharziasis Laboratory, Charlottenlund, Denemarken)

Financial support:

Contents

Geographical distribution and epidemiology of Oesophagos-tomum bifurcum and hookworm infections in humans in Togo

Diagnosis of Oesophagostomum bifurcum and hookworm in-fections in humans: Day-to-day and within-specimen varia-tion of larval counts

Antigen specific IgG4 and IgE responses in individuals in-fected with Oesophagostomum bifurcum and hookworm Prevalences of Oesophagostomum bifurcum and Necator americanus infections using specific PCR amplification of DNA from fecal samples.

The pattern of infection and re-infection with Oesophagos-tomum bifurcum and hookworm following treatment in northern Togo

The capacity of L3 larvae of Oesophagostomum bifurcum to

survive adverse conditions

Parasite-specific cellular immune responsiveness in humans infected with Necator americanus and Oesophagostomum bifurcum