University of Groningen
A geriatric perspective on chronic kidney disease Bos, Harmke Anthonia
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date:
2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Bos, H. A. (2019). A geriatric perspective on chronic kidney disease: The three M's. Rijksuniversiteit Groningen.
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Download date: 27-06-2021
A geriatric perspective on chronic kidney disease
The three M’s
Harmke A. Polinder-Bos
Harmke A. Polinder-Bos
A geriatric perspective on chronic kidney disease. The three M’s PhD dissertation University of Groningen, The Netherlands
Financial support by the University of Groningen, Graduate School of Medical Sciences, Alzheimer Nederland, Beter Healthcare B.V., Chipsoft, Dialysis Center Groningen, Dutch Kidney Foundation, Fresenius Medical Care B.V., HMZ Fashiongroup B.V. (Lemon & Soda), and Nekst IT B.V. for the printing of this thesis is gratefully acknowledged.
ISBN: 978-94-034-1174-3 (printed version) ISBN: 978-94-034-1173-6 (digital version)
Cover design: Ilse Modder, www.ilsemodder.nl Lay out and printed by: Gildeprint, Enschede
© Copyright 2018 H.A. Polinder-Bos. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanically, by photocopying, recording or otherwise, without the permission of the author.
A geriatric perspective on chronic kidney disease
The three M’s
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promo- ties
De openbare verdediging zal plaatsvinden op woensdag 9 januari 2019 om 12.45 uur
door
Harmke Anthonia Bos geboren op 14 juni 1984
te Zeist
A geriatric perspective on chronic kidney disease
The three M’s
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties De openbare verdediging zal plaatsvinden op
woensdag 9 januari 2019 om 12.45 uur
door
Harmke Anthonia Bos
geboren op 14 juni 1984 te Zeist
Promotores
Prof. dr. C.A.J.M. Gaillard Prof. dr. R.T. Gansevoort
Copromotor Dr. C.F.M. Franssen
Beoordelingscommissie Prof. dr. S.E.J.A. de Rooij Prof. dr. S.J. Berger Prof. dr. P.M. ter Wee
Paranimfen
E.A. Luitwieler-Blok, MSc Drs. A.C. Slotboom-Bosker
CONTENTS
Chapter 1 Introduction 7
PART I Muscle
Chapter 2 Lower body mass index and mortality risk in older adults starting dialysis
31 Sci Rep 2018; 8(1):12858
Chapter 3 Low urinary creatinine excretion is associated with self- reported frailty in patients with advanced chronic kidney disease
55
Kidney Int Rep 2017;2:676-685
Chapter 4 Creatinine synthesis rate and associations with muscle strength and self-reported physical health in dialysis patients
83
Submitted PART II Mobility
Chapter 5 High fall incidence and fracture rate in elderly dialysis patients 107 Neth J of Med 2014;72(10):509-515
PART III Mind
Chapter 6 Hemodialysis induces an acute decline in cerebral blood flow in elderly patients
125 J Am Soc Nephrol 2018;4:1317-1325
Chapter 7 Changes in cerebral oxygenation and cerebral blood flow during hemodialysis – a simultaneous near-infrared spectroscopy and positron emission tomography study
155
Accepted for publication in J Cereb Blood Flow Metab
Chapter 8 Summary, general discussion and future perspectives 185
Nederlandse samenvatting - summary in Dutch 213
Dankwoord - Acknowledgements 225
About the author 233
List of publications 237
