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University of Groningen

The clinical presentation, neurcognition and neural correlates of children with a tic disorder

Openneer, Thaïra

DOI:

10.33612/diss.173528953

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Openneer, T. (2021). The clinical presentation, neurcognition and neural correlates of children with a tic disorder. University of Groningen. https://doi.org/10.33612/diss.173528953

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The clinical presentation,

neurocognition and neural correlates

of children with a tic disorder

Thaïra J.C. Openneer

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The research described in this thesis was carried out at the Department of Child and Adolescent Psychiatry, Groningen, University of Groningen, University Medical Center Groningen, The Netherlands. This work was supported by the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement 278367 (EMTICS); the European Community's Seventh Framework Programme FP7/2007–2013 under grant agreement 278948 (TACTICS); and FP7-PEOPLE-2012-ITN under grant agreement 316978 (TS-EUROTRAIN).

Print: Ridderprint | www.ridderprint.nl. © 2021, Thaïra. J. C. Openneer

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system of any nature, or transmitted in any form or by any means, electronic, mechanical, now known or hereafter invented, including photocopying or recording, without prior written permission from the author.

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The clinical presentation,

neurocognition and neural

correlates of children with a tic

disorder

Proefschrift

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op dinsdag 6 juli 2021 om 11.00 uur

door

Thaïra Openneer

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Promotor

Prof. dr. P.J. Hoekstra

Copromotores

Dr. A. Dietrich Dr. D. van der Meer Dr. J.B.C. Marsman

Beoordelingscommissie

Prof. dr. D.A.J.P. Denys Prof. dr. D.C. Cath Prof. dr. M.H. Nauta

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Table of contents

Chapter 1.

7

General introduction

Chapter 2.

27

Clinical precursors of tics: An EMTICS study

Chapter 3.

65

The Premonitory Urge for Tics Scale in a large sample of children and adolescents: Psychometric properties in a developmental context. An EMTICS study

Chapter 4.

99

Executive function in children with Tourette syndrome and attention-deficit/hyperactivity disorder: Cross-disorder or unique impairments?

Chapter 5.

129

Impaired response inhibition during a stop-signal task in children with Tourette syndrome is related to ADHD symptoms: A functional magnetic resonance imaging study

Chapter 6.

157

A graph theory study of resting-state functional connectivity in children with Tourette syndrome

Chapter 7.

Summary and general discussion 183

Appendices

Appendix 1. Internationale samenwerking geeft nieuwe impulsen aan Tourette

onderzoek 208

Appendix 2. Nederlandse samenvatting 215

Appendix 3. Propositions 221

Appendix 4. Acknowledgements (dankwoord) 222

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