Cushing's Syndrome : hormonal secretion patterns, treatment and
outcome.
Aken, M.O. van
Citation
Aken, M. O. van. (2005, March 17). Cushing's Syndrome : hormonal secretion patterns,
treatment and outcome. Retrieved from https://hdl.handle.net/1887/3748
Version:
Corrected Publisher’s Version
License:
Licence agreement concerning inclusion of doctoral thesis in the
Institutional Repository of the University of Leiden
Downloaded from:
https://hdl.handle.net/1887/3748
Cushing’s Syndrome
postz egel met afbeelding van H. Cushing, in de serie “ G reat A meric ans” (19 8 8 ).
Cushing’s Syndrome
Hormonal secretion patterns, treatment and outcome
P roefschrift
ter verkrijging van de graad van Doctor aan de U niversiteit L eiden,
op gezag van de
Rector M agnifi cus Dr. D.D. B reimer, hoogleraar in de faculteit der W iskunde en N atuurw etenschappen en die der Geneeskunde,
volgens besluit van het College voor Promoties te verdedigen op donderdag
17 maart 2 0 0 5 klokke 14 .15 uur door
Promotores: Prof. dr. J.A. Romijn
Prof. dr. S .W.J. Lamberts, E rasmus Universiteit Rotterdam Copromotor: dr. W.W. de Herder, E rasmus Universiteit Rotterdam
Referent: Prof. dr. A.R.M.M. Hermus, Universitair Medisch Centrum S t. Radboud
Overige leden: Prof. dr. E .R. de K loet Prof. dr. S .E . Papapoulos
Prof. dr. H.A.P. Pols, E rasmus Universiteit Rotterdam dr. F . Roelfsema
Aan Manon
CONTENTS
Chapter 1 Introduction Chapter 2
Irregular and freq uent cortisol secretory episodes with preserved diurnal rhythmicity in primary adrenal Cushing’s syndrome.
Journal of Clinical Endocrinology and Metabolism, online publication dec. 2 0 0 4
Chapter 3
Growth hormone secretion in primary adrenal Cushing’s syndrome is disorderly and inversely correlated with body mass index .
A merican Journal of P h ysiology: Endocrinology and Metabolism 2 0 0 5 : 2 8 8 (1 ); E6 3 -7 0
Chapter 4
Profound amplifi cation of secretory-burst mass and anomalous regularity of ACT H secretory process in patients with Nelson’s syndrome compared with Cushing’s disease.
Clinical Endocrinology 2 0 0 4 :6 0 ;7 6 5 -7 7 2 Chapter 5
Salivary cortisol in the diagnosis of Cushing’s syndrome. P ublish ed in part in Clinical Ch emistry 2 0 0 3 :4 9 (8 );1 4 0 8 -1 4 0 9 Chapter 6
Risk factors for meningitis after transsphenoidal surgery. Clinical I nfectious D iseases 1 9 9 7 ;2 5 :8 5 2 -6
Chapter 7
Cerebrospinal fl uid leakage during transsphenoidal surgery: postoperative ex ternal lumbar drainage reduces the risk for meningitis.
P ituitary 2 0 0 4 ;7 : 9 3 -9 7 Chapter 8
Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing’s disease.
Long-term predictive value of postsurgical cortisol concentrations for cure and risk of recurrence in Cushing’s disease.
Journal of Clinical Endocrinology and Metabolism 2003: 88;5858-5864
Chapter 10
Decreased quality of life in patients despite long-term biochemical cure of Cushing’s disease
S ubmitted Chapter 11
