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Cover Page

The handle http://hdl.handle.net/1887/20407 holds various files of this Leiden University dissertation.

Author: Maas, Jacinta

Title: Mean systemic filling pressure : from Guyton to the ICU Date: 2013-01-17

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Mean systemic fi lling pressure

from Guyton to the ICU

Jacinta Maas

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ISBN: 978 - 90 - 9027060 - 9

Cover photo: beach at Burgh-Haamstede (Zeeland) by Jacinta Maas Design cover by R.A.J.M. de Best and J. van Paassen

Printed by UFB /Grafi sche Producties, Leiden

© 2013, J.J. Maas, Leiden, The Netherlands

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Mean systemic fi lling pressure

from Guyton to the ICU

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden,

op gezag van Rector Magnifi cus prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties

te verdedigen op donderdag 17 januari 2013 klokke 11.15 uur

door

Jacomina Johanna (Jacinta) Maas geboren te Hillegom

in 1966

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Promotiecommissie

Promotores: Prof. Dr. E. de Jonge Prof. Dr. L.P.H.J. Aarts Co-promotor: Dr. J.R.C. Jansen

Overige leden: Prof. Dr. A.B.J. Groeneveld (Erasmus Universiteit Rotterdam) Prof. Dr. J.G. van der Hoeven (Universiteit Nijmegen)

Prof. Dr. R.J.M. Klautz

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Contents

Chapter 1 General introduction and outline of this thesis Chapter 2 Bedside assessment of mean systemic fi lling pressure Chapter 3 Assessment of venous return curve and mean systemic fi lling

pressure in postoperative cardiac surgery patients Chapter 4 Evaluation of mean systemic fi lling pressure from pulse

contour cardiac output and central venous pressure

Chapter 5 Estimation of mean systemic fi lling pressure in postoperative cardiac surgery patients with three methods

Chapter 6 Arm occlusion pressure is a useful predictor of an increase

in cardiac output after fl uid loading following cardiac surgery Chapter 7 Bedside assessment of total systemic vascular compliance,

stressed volume and cardiac function curves in ICU patients Chapter 8 Determination of vascular waterfall phenomenon by bedside

measurement of mean systemic fi lling pressure and critical

closing pressure in the ICU

Chapter 9 Partitioning the resistances along the vascular tree: effects of dobutamine and hypovolemia in piglets with an intact

circulation

Chapter 10 Cardiac output response to norepinephrine in ICU patients:

interpretation with venous return and cardiac function curves Chapter 11 Final considerations and clinical implications

Chapter 12 Summary/Samenvatting Abbreviations

7 25

37

51

65

79

89

107

123

137 153 163 175

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Curriculum Vitae

List of publications

Dankwoord

177 179 181

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