• No results found

Non-ribose ligands for the human adenosine A1 receptor Klaasse, E.C.

N/A
N/A
Protected

Academic year: 2021

Share "Non-ribose ligands for the human adenosine A1 receptor Klaasse, E.C."

Copied!
2
0
0

Bezig met laden.... (Bekijk nu de volledige tekst)

Hele tekst

(1)

Non-ribose ligands for the human adenosine A1 receptor

Klaasse, E.C.

Citation

Klaasse, E. C. (2008, June 10). Non-ribose ligands for the human adenosine A1 receptor. Retrieved from https://hdl.handle.net/1887/12936

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded

from: https://hdl.handle.net/1887/12936

Note: To cite this publication please use the final published version (if applicable).

(2)

167245-L_plaat1_9-5-2008_9:18:41

167245-L_plaat1_9-5-2008_9:18:41

Non-ribose Ligands for the Human Adenosine A 1 receptor

Affinities, activities, allosteric modulation

& internalization

Elisabeth Klaasse

Elis abe th K laa sse 200 8

Uitnodiging

voor het bijwonen van de promotie van

Elisabeth Klaasse

dinsdag op 10 juni 2008 om 13.45 uur in de Lokhorstkerk,

Pieterskerkstraat 1 te Leiden

Gezien het beperkte aantal plaatsen wordt alleen toegang

verleend tot de promotie op vertoon van een toegangskaart

Houdt u rekening met tijdrovende parkeerproblemen

in de binnenstad

De paranimfen:

Corine Barnhoorn-Klaasse 071-4010830

Agatha Kuijt 071-4020461

---

---

Elisabeth Klaasse Merschpad 4 2231 AB Rijnsburg 071-4075361/06-51024857 elisabethklaasse@hotmail.com

No n-r ibo se L igands f or the Human A de no sine A

1

recept or

Non-ribose Ligands for the Human Adenosine A 1 receptor

Affinities, activities, allosteric modulation

& internalization

Elisabeth Klaasse

Elis abe th K laa sse 200 8

Uitnodiging

voor het bijwonen van de promotie van

Elisabeth Klaasse

dinsdag op 10 juni 2008 om 13.45 uur in de Lokhorstkerk,

Pieterskerkstraat 1 te Leiden

Gezien het beperkte aantal plaatsen wordt alleen toegang

verleend tot de promotie op vertoon van een toegangskaart

Houdt u rekening met tijdrovende parkeerproblemen

in de binnenstad

De paranimfen:

Corine Barnhoorn-Klaasse 071-4010830

Agatha Kuijt 071-4020461

---

---

Elisabeth Klaasse Merschpad 4 2231 AB Rijnsburg 071-4075361/06-51024857 elisabethklaasse@hotmail.com

No n-r ibo se L igands f or the Human A de no sine A

1

recept or

In-RIP-Color-ID-90_Agfa.eps

Referenties

GERELATEERDE DOCUMENTEN

Receptor trafficking can be regulated in different ways (Figure 2.3): a) the receptor resides mainly in lipid rafts/caveolae and enters the cell via this pathway by default; b)

Moreover, for all A 1 -G i D fusion proteins tested, the maximal stimulation of basal [ 35 S]GTP JS binding was significantly larger than the maximal CPA-induced effect with

These binding experiments showed us that the human adenosine A 1 YFP receptor retains its pharmacological profile and that the allosteric modulator PD81,723 and SCH-202676 have the

Modulation of forskolin-induced cAMP production in CHO cells stably expressing the human adenosine A 1 receptor, after exposure to reference ligands (CPA, DPCPX, N0840) and

CHO cells stably expressing the human adenosine A 1 YFP receptor were exposed to the reference agonist CPA, to LUF6037 and to the inverse agonist DPCPX at a concentration of 4 PM

To characterize the new, non-adenosine radioligand [ 3 H]LUF5834, kinetic association and dissociation experiments on membranes of CHO cells stably expressing the wt human adenosine A

To further explore the composition of the A 1 R population and the behaviour of [ 3 H]LUF5834, radioligand binding studies with a range of reference ligands representing full

LUF6037 recognized two binding states/sites on the human adenosine A 1 receptor with picomolar and nanomolar affinity, both much higher than the reference agonist CPA.. Just like