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Antimicrobial compounds as side products from the agricultural

processing industry

Sumthong, P.

Citation

Sumthong, P. (2007, June 19). Antimicrobial compounds as side products from the

agricultural processing industry. Division of Pharmacognosy, Section of Metabolomics,

Institute of Biology, Faculty of Science, Leiden University. Retrieved from

https://hdl.handle.net/1887/12086

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the

Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/12086

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Antimicrobial compounds as side products

from the agricultural processing industry

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Pattarawadee Sumthong

Antimicrobial compounds as side products from the agricultural processing industry ISBN 978-90-9021941-7

Printed by PrintPartners Ipskamp B.V., Amsterdam, The Netherlands

The cover was designed by Teerasak Techakitkhachon.

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Antimicrobial compounds as side products

from the agricultural processing industry

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P. F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op dinsdag 19 juni 2007

klokke 13.45 uur

door

Pattarawadee Sumthong

geboren te Bangkok (Thailand) in 1976

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Promotiecommissie

Promotor Prof. dr. R. Verpoorte Referent Prof. dr. L. Bohlin

(Uppsala University, Sweden)

Overige Leden Prof. dr. C. A. M. J. J. van den Hondel Prof. dr. P. J. J. Hooykaas

Dr. Y. H. Choi Dr. A. F. J. Ram

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Contents

Chapter 1 General introduction 1 Chapter 2 Developing antimicrobial compounds from natural sources 9 Chapter 3 Screening for antimicrobial activity 19 Chapter 4 Isolation and elucidation of quinones in Tectona grandis 33 Chapter 5 Induction of fungal cell wall stress 43 Chapter 6 Anthranilate synthase inhibition 49 Chapter 7 Anti-wood rot activity 57 Chapter 8 Future perspectives in biodiversity exploration 67

Summary 73

Samevatting 77



(Summary in Thai)

81

References 87

Curriculum vitae 107 Acknowledgements 109

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