University of Groningen
The Clinical Value of HDL Function Measurements
Ebtehaj, Sanam
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
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Ebtehaj, S. (2019). The Clinical Value of HDL Function Measurements. University of Groningen.
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The Clinical Value of HDL
Function Measurements
This project was financially supported by:
University Medical Center Groningen, Graduate School of Medical Science
Cover and layout: Sanam Ebtehaj
Print by: Ridderprint BV, the Netherlands
Copyright ã 2019 Sanam Ebtehaj
All rights reserved. No part of this publication may be reproduced, stored or
transmitted in any form or by any means, electronically or mechanically,
including photocopy, recording or otherwise without the written permission
of the author.
ISBN: 978-94-034-1740-0 (printed)
ISBN: 978-94-034-1739-4 (digital)
The Clinical Value of HDL
Function Measurements
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the Rector Magnificus Prof. E. Sterken
and in accordance with the decision by the College of Deans. This thesis will be defended in public on
Wednesday 3 July 2019 at 9.00 hours
by
Sanam Ebtehaj
born on 19 September 1983 in Tabriz, Iran
Supervisors
Prof. dr. F. Kuipers Prof. dr. U.J.F. Tietge
Assessment Committee
Prof. dr. J.A. Kuivenhoven Prof. dr. S.J.L. Bakker Prof. dr. G. Theilmeier
Paranymphs
Shiva Shajari Ali Saeed
CONTENTS
Chapter 1.
General Introduction
Chapter 2. HDL cholesterol efflux does not predict cardiovascular risk
in hemodialysis patients
Chapter 3. The predictive value of the anti-oxidative function of HDL for cardiovascular disease and graft failure in renal transplant recipients
Chapter 4. The anti-inflammatory function of HDL is impaired in type 2 diabetes: the role of hyperglycemia, paraoxonase-1, and low-grade inflammation
Chapter 5. HDL function measurements provide clinical information independent of established cardiovascular risk metrics - a cross-sectional study from the PROCAM-CT cohort
Chapter 6. General discussion and future perspective
Chapter 7. Summary Appendix. Acknowledments List of publications 9 39 61 85 103 123 141 149 154
